重度肥胖患者腹腔镜胃旁路术后味觉的改变

目的:探讨腹腔镜Roux-en-Y胃旁路术(laparoscopic Roux-en-Y gastric bypass,LRYGB)对重度肥胖患者味觉的影响。方法:前瞻性地选择13例BMI平均为(38.6±3)kg/m2的重度肥胖患者作为研究对象,利用味觉问卷评估患者LRYGB术前及术后3个月的味觉变化情况。结果:术后12人(92.3%)饮食后口味发生了变化,较术前2人(15.4%)差异有统计学意义(P=0.006),患者术后食用甜食、肉类、脂类较术前明显降低,分别为(6.31±1.25)vs.(7.77±1.09)(P=0.000),(6.77±1.01)vs.(8.54±1.13)(P=0.000),(5.85±1.28)vs.(6.77±1.3)(P=0.004),手术前后在"甜食口感下降、咸食口感下降及总体口感下降"3方面均存在明显差异,分别为:0 vs.61.5%(P=0.008),0 vs.46.2%(P=0.031),15.4%vs.84.6%(P=0.039),肥胖患者术后对"味觉在享受食物的重要性"的认可度,由术前的(6.92±1.38)上升至(8.46±0.78),差异有统计学意义(P=0.000)。结论:术后患者对食物、饮料的口味发生了变化,并且出现部分味觉受损,尤其对甜食、咸食、总体口感的下降影响了肥胖患者LRYGB术后食物的摄入量。

Taste change after laparoscopic Roux-en-Y gastric bypass surgery for clinically severe obesity

Objective：To investigate the taste change following laparoscopic Roux-en-Y gastric bypass （LRYGB） for clinically severe obesity. Methods：A total of 13 clinically severe obesity patients whose mean baseline BMI was （38.6± 3 ） kg/m^2 underwent LRYGB. They were proactively selected as research object, and filled in taste change questionnaires before and 3 months after surgery. Results： More postoperative group patients （92.3%） than preoperative group （ 15.4% ） reported a change in the taste of food or bever- ages （P = 0. 006）. The consumption of sweets, meat and fat of the postoperative group was significantly lower than those of the preoper- ative group, respectively （6.31± 1.25 ） vs. （7.77 ± 1.09） （P = 0. 000）, （6.77 ±1.01 ） vs. （ 8.54±1.13 ） （ P = 0. 000）, （5.85 ± 1.28 ） vs. （6.77±1.3 ） （ P = 0. 004） ]. Significantly more postoperative group patients developed a decreased taste for sweet, salt and overall foods eompared with preoperative group,respeetively 0% vs. 61.5% （P =0. 008） ,0% vs. 46.2% （P =0. 031 ）, 15.4% vs. 84.6% （ P = 0. 039） ]. There was signifieant increase in the score of “the importance of taste in the enjoyment of food ”between pre- and postoperative group （ 6.92 ± 1.38 ） vs. （ 8.46 ± 0.78 ） , P = 0.000 ]. Conclusions ： Taste change appeares in the taste of food and beverages after surgery, even taste damages partly. Espeeially, the decline in the taste of sweets, salt and overall foods decreases the food intake of obesity patients after LRYGB.