仙灵骨葆合阿仑磷酸钠治疗绝经后骨质疏松症的临床观察

目的:观察使用仙灵骨葆合阿仑磷酸钠治疗绝经后骨质疏松症的疗效。方法:156例绝经后骨质疏松患者随机分为3组:治疗组与对照组A、B,每组52例,治疗组使用仙灵骨葆胶囊合阿仑磷酸钠,对照组A单纯使用阿仑磷酸钠,对照组B单纯使用仙灵骨葆胶囊治疗。评价治疗前、治疗3个月和治疗6个月后的疼痛评分情况,并观察治疗6月前后骨密度的改变。结果:3组治疗3个月后与治疗前比较,疼痛积分均有极显著的改善(均P<0.01),治疗组与两对照组相比,疼痛积分改善更明显(P<0.01,P<0.05);治疗6个月后,3组的疼痛积分改善更显著(均P<0.001),治疗组与两对照组相比,疼痛积分改善更明显(P<0.01,P<0.01)。治疗组腰椎与股骨颈WARD三角区的骨密度与治疗前有显著的统计学意义(均P<0.01),而两对照组的骨密度与治疗前的差异不明显。结论:仙灵骨葆和阿仑磷酸钠合用对治疗骨质疏松有良好疗效。

Clinical Observation of Xianlinggubao Plus Alendronate on Postmenopausal Osteoporosis

Objective:To investigate the effects of Xianlinggubao plus alendronate on postmenopausal osteoporosis,and their safety and adaptation included.Methods:By random number generating method,156 patients with postmenopausal osteoporosis were randomly divided into a treatment group treated with Xianlinggubao capsule plus alendronate,control group A only with Xianlinggubao capsule,and control group B only with alendronate.The pain of the patient before treatment,3 months and 6 months after treatment were assessed....