颅内血管狭窄程度和ABCD2评分与短暂性脑缺血发作患者近期预后的相关性研究

目的 探讨颅内血管狭窄程度和ABCD2评分与短暂性脑缺血发作患者近期预后的相关性.方法 选取2015年1月至2016年9月期间我院神经内科收治的60例短暂性脑缺血发作患者作为研究对象,均给予CT血管成像(CTA)检查和ABCD2评分,分析患者颅内血管狭窄程度及ABCD2评分与近期预后的相关性.结果 CTA检查结果显示,60例患者中44例(73.3%)存在不同程度的颅内血管狭窄,其中正常及轻度狭窄35例(58.3%)、中度狭窄15例(25.0%)、重度狭窄10例(16.7%);根据ABCD2评分法评估显示,低危组21例(35.0%)、中高危组39例(65.0%);60例TIA患者7 d内13例发生脑梗死,其中颅内血管轻度狭窄1例(1.7%)、中度狭窄6例(10.0%)、重度狭窄6例(10.0%),与轻度狭窄患者比较,中度狭窄及重度狭窄患者发生脑梗死概率明显增高,差异有统计学意义(P<0.05);中高危组患者发生脑梗死的几率为30.8%,较低危组患者的4.8%明显增高,差异有统计学意义(P<0.05).结论 颅内血管狭窄、ABCD2评分都是短暂性脑缺血发作患者近期预后的重要评估指标.

Correlation between intracranial vessel stenosis degree,ABCD2 score in patients with transient ischemic attack and short-term prognosis

Objective To study the correlation between intracranial vessel stenosis degree, ABCD2 score in patients with transient ischemic attack (TIA) and short-term prognosis. Methods Sixty patients with TIA in Depart-ment of Neurology of Beijing Jiangong Hospital from January 2015 to September 2016 were regarded as the research subjects. Both CT vascular imaging examinations and ABCD2 scores were performed in the subjects. The correlation be-tween intracranial vessel stenosis degree, ABCD2 score and short-term prognosis were analyzed. Results CTA exami-nation showed that 44 of the 60 patients had intracranial vessel stenosis (73.3%) in different degree, and there were 35 cases of normal and mild vessel stenosis (58.3%), 15 cases of moderate vessel stenosis (25.0%), and 10 cases of severe vessel stenosis (16.7%). According to ABCD2 score method, 21 cases of low risk group (35.0%) and 39 cases of medi-um-high risk group (65.0%) were included in 60 patients. Thirteen cases progressed to cerebral infarction in 7 d after on-set, which included 1 case with mild vessel stenosis (1.7%), 6 cases with moderate vessel stenois (10.0%), and 6 cases of severe vessel stenois (10.0%). Compared with the mild vessel stenosis, the incidence of cerebral infarction was signifi-cantly increased in patients with moderate and severe vessel stenosis with statistical difference (P<0.05). The incidence of cerebral infarction of medium-high risk group (30.8%) was obviously higher that in the low risk group (4.8%) (P<0.05). Conclusion The intracranial vessel stenosis degree and ABCD2 score can be the important predicting index for evaluating short-term prognosis for patients with TIA .