Pulmonary plasmacytoma: about two new cases and review of the literature |
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Authors: | Etienne G Grenouillet M Ghiringhelli C Vatan R Lazaro E Germain P Mercié P Longy-Boursier M |
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Affiliation: | Service de médecine interne et maladies tropicales, groupe hospitalier Saint-André, 1, rue Jean-Burguet, 33075 Bordeaux, France. gabriel.etienne@chu-bordeaux.fr |
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Abstract: | INTRODUCTION: Extramedullary plasmacytoma is an uncommon plasma cell malignancy mainly located to the upper aerodigestive tract. Primary pulmonary plasmacytoma is extremely rare. EXEGESIS: We report two new cases of primary pulmonary plasmacytoma and then proceed to a review of the literature concerning 35 similar cases previously described. CONCLUSION: Complete or partial responses were obtained in 24 cases (65%). Five patients (14%) have developed multiple myeloma within 3 years following plasmacytoma diagnostic. In spite of sustained responses with radiotherapy or chemotherapy, surgical resection while feasible remains the first therapeutic option. |
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