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Re-irradiation of metastatic spinal cord compression: A feasibility study by volumetric-modulated arc radiotherapy for in-field recurrence creating a dosimetric hole on the central canal |
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| Authors: | Pietro Mancosu Piera Navarria Luca Cozzi Paola Lattuada Gaetano Urso Marta Scorsetti |
| Affiliation: | a IRCCS Istituto Clinico Humanitas, Radiation Oncology, Rozzano, Italy b Oncology Institute of Southern Switzerland, Medical Physics Unit, Bellinzona, Switzerland c IRCCS Istituto Clinico Humanitas, Medical Oncology, Rozzano, Italy |
| Abstract: | When local recurrences arise within an irradiated region involving metastatic spinal cord compression, the dose limit to the spinal cord reduces the chance to re-treat the patient by 3D-conformational RT technique. The possibility of using volumetric modulated arc RT by RapidArc was evaluated for dose sparing at spinal cord level and preserving target coverage. A clinically satisfactory PTV coverage and dose sparing to the spinal cord were obtained. An upcoming trial on patients will provide clinical outcomes. |
| Keywords: | RapidArc Metastatic spinal cord compression&mdash MSCC Re-irradiation Radiotherapy Volumetric modulated arc therapy |
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