抗生素预防择期腹腔镜胆囊切除术后感染性并发症的研究

目的:探讨择期腹腔镜胆囊切除术预防性使用抗生素的必要性和影响。方法:麻醉诱导后,A组患者(n=141)予以1g先锋V号,B组患者(n=136)则不予抗生素,比较分析两组患者的手术过程和治疗结果。结果:277例患者的总感染率为1.1%(A组0.7%,B组1.5%),组间无统计学差异。研究中未发现任何危险因素可导致外科部位感染发生率升高。结论:预防性使用抗生素并不能降低择期腹腔镜胆囊切除术感染性并发症的发生率。

Study on the prophylactic antibiotics on postoperative infectious complications in elective laparoscopic cholecystectomy

Objective:To investigate the necessity and influence for prophylactic antibiotics on postoperative infectious complications in elective laparoscopic cholecystectomy(LC).Methods:At the time of induction of anesthesia,group A patients(n=141) received 1g cefazolin,and group B patients received nothing.Patients characteristics general operative course and outcome were compared and analyzed.Results:The rate of infectious was 1.1% for total 277 patients(0.7% for group A and 1.5% for group B).No significant difference in infection complications were found in two groups.Also no risk factors contributing to infectious complications could be found.Conclusions:The prophylactic antibiotics in elective LC can not decrease the postoperative infectious complications.