血管免疫母细胞T细胞淋巴瘤^18MF-FDGPET/CT的影像表现及其在临床分期中的价值

目的分析血管免疫母细胞T细胞淋巴瘤（angioimmunoblasticT-celllymphoma，AITL）^18F-FDGPET/CT的影像学表现及分布规律，探讨其在临床分期中的价值。方法回顾性分析22例AITL患者的^18F-FDGPET/CT显像结果，评价其在临床分期中的价值。结果（1）AITL结内侵犯的^18F-FDGPET/CT影像学表现：①全身弥漫性分布：左右对称性分布9例（40．9％），左右不对称性分布2例（9．1％）；②多部位散在分布：与淋巴链走行有关4例（18．2％），与淋巴链走行无关5例（22．7％）；③单部位局限性分布2例（9．1％）；（2）AITL结外侵犯的^18F-FDGPET／CT影像学表现：鼻咽部侵犯最常见有10例，其余依次为口咽8例，脾脏8例，骨骼及骨髓5例，胃肠道4例，肺、胸膜及皮肤各2例，乳腺及颅内侵犯各1例；（3）在AITL分期中的价值：PET/CT显像改变了4例（18．2％，4/22）患者的分期，均为分期上调。结论血管免疫母细胞T细胞淋巴瘤呈”F-FDG高摄取；其在病灶检测及分期方面，^18F-FDGPET/CT显像有优势。

^18 F-FDG PET/CT imaging findings of angioimmunoblastic T-cell lymphoma and its value in clinical staging

Objective To analyse the imaging findings and distribution of ^18F-FDG PET/CT in angioimmunoblastic T cell lymphoma （AITL）, and to evaluate the value of ^18F-FDG PET/CT in the clinical staging. Methods We retrospective ly analysed ^18 F-FDG PET/CT imaging findings of 22 patients with AITL, and evaluated its value in the clinical staging. Results （）1The imaging findings and distribution of ^18F-FDG PET/CT in AITL with nodal involvement. ① Whole-body multiple lesions with diffuse distribution： symmetrical distribution was observed in 9 of 22 patients （40.9%）, and asym metrical distribution was observed in 2 of 22 patients （9.1 %） ; ② Multi-lesions in multi-locations with scattering distribu tion： lesions traveling along the lymphatic chain were observed in 4 of 22 patients （18.2%）, and lesions without traveling along the lymphatic chain were observed in 5 of 22 patients （22.70/00） ; ③ Limited distribution was observed in 2 of 22 pa tients （9.1 %）. （2） The imaging findings of JSF-FDG PET/CT in AITL with extranodal involvement. The more frequent sites of the lymphoma lesions were nasopharynx （10/22）, oropharynx （8/22）, spleen （8/22）, bone and bone marrow （5/ 22）, gastrointestinal （4/22）, lung （2/22）, pleura （2/22）, skin （2/22）, breast （1/22）, brain （1/22）. （3） The value of 18 F-FDG PET/CT imaging in the clinical staging of AITL. The stage of disease was changed in four patients on the basis of 18F-FDG PET/CT. All patients were upstaged. Conclusion The lesions of AITL are ^18F-FDG avid, and PET/CT seems to be useful in detecting and staging of this disease.