血管免疫母细胞T细胞淋巴瘤^18MF-FDGPET/CT的影像表现及其在临床分期中的价值 |
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引用本文: | 丁重阳,李天女,杨文平,孙晋,丁英勇. 血管免疫母细胞T细胞淋巴瘤^18MF-FDGPET/CT的影像表现及其在临床分期中的价值[J]. 医学影像学杂志, 2013, 0(12): 1887-1890 |
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作者姓名: | 丁重阳 李天女 杨文平 孙晋 丁英勇 |
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作者单位: | 南京医科大学第一附属医院核医学科,江苏南京210029 |
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摘 要: | 目的分析血管免疫母细胞T细胞淋巴瘤(angioimmunoblasticT-celllymphoma,AITL)^18F-FDGPET/CT的影像学表现及分布规律,探讨其在临床分期中的价值。方法回顾性分析22例AITL患者的^18F-FDGPET/CT显像结果,评价其在临床分期中的价值。结果(1)AITL结内侵犯的^18F-FDGPET/CT影像学表现:①全身弥漫性分布:左右对称性分布9例(40.9%),左右不对称性分布2例(9.1%);②多部位散在分布:与淋巴链走行有关4例(18.2%),与淋巴链走行无关5例(22.7%);③单部位局限性分布2例(9.1%);(2)AITL结外侵犯的^18F-FDGPET/CT影像学表现:鼻咽部侵犯最常见有10例,其余依次为口咽8例,脾脏8例,骨骼及骨髓5例,胃肠道4例,肺、胸膜及皮肤各2例,乳腺及颅内侵犯各1例;(3)在AITL分期中的价值:PET/CT显像改变了4例(18.2%,4/22)患者的分期,均为分期上调。结论血管免疫母细胞T细胞淋巴瘤呈”F-FDG高摄取;其在病灶检测及分期方面,^18F-FDGPET/CT显像有优势。
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关 键 词: | 血管免疫母细胞T细胞淋巴瘤 正电子发射型计算机断层扫描 ^18氟-氟代脱氧葡萄糖 临床分期 |
^18 F-FDG PET/CT imaging findings of angioimmunoblastic T-cell lymphoma and its value in clinical staging |
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Affiliation: | DING Chong-yang , LI Tian-nv, YANG Wen-ping, SUN Jin , DING Qi-yong Department of Nuclear Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, P. R. China |
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Abstract: | Objective To analyse the imaging findings and distribution of ^18F-FDG PET/CT in angioimmunoblastic T cell lymphoma (AITL), and to evaluate the value of ^18F-FDG PET/CT in the clinical staging. Methods We retrospective ly analysed ^18 F-FDG PET/CT imaging findings of 22 patients with AITL, and evaluated its value in the clinical staging. Results ()1The imaging findings and distribution of ^18F-FDG PET/CT in AITL with nodal involvement. ① Whole-body multiple lesions with diffuse distribution: symmetrical distribution was observed in 9 of 22 patients (40.9%), and asym metrical distribution was observed in 2 of 22 patients (9.1 %) ; ② Multi-lesions in multi-locations with scattering distribu tion: lesions traveling along the lymphatic chain were observed in 4 of 22 patients (18.2%), and lesions without traveling along the lymphatic chain were observed in 5 of 22 patients (22.70/00) ; ③ Limited distribution was observed in 2 of 22 pa tients (9.1 %). (2) The imaging findings of JSF-FDG PET/CT in AITL with extranodal involvement. The more frequent sites of the lymphoma lesions were nasopharynx (10/22), oropharynx (8/22), spleen (8/22), bone and bone marrow (5/ 22), gastrointestinal (4/22), lung (2/22), pleura (2/22), skin (2/22), breast (1/22), brain (1/22). (3) The value of 18 F-FDG PET/CT imaging in the clinical staging of AITL. The stage of disease was changed in four patients on the basis of 18F-FDG PET/CT. All patients were upstaged. Conclusion The lesions of AITL are ^18F-FDG avid, and PET/CT seems to be useful in detecting and staging of this disease. |
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Keywords: | Angioimmunoblastic T-cell lymphoma Positron emission tomography Fluorine-18 fluoro-deoxy-glucose Clinical staging |
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