| 口服微载体药物递送系统及其在中药研究中的应用 |
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| 引用本文： | 毕肖林,刘璇,祖强,狄留庆. 口服微载体药物递送系统及其在中药研究中的应用[J]. 中国中药杂志, 2013, 38(21): 3638-3644 |
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| 作者姓名： | 毕肖林 刘璇 祖强 狄留庆 |
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| 作者单位： | 南京中医药大学 药学院, 江苏 南京 210023;江苏省中药高效给药系统工程技术研究中心, 江苏 南京 210023;南京市中药微丸产业化工程技术研究中心, 江苏 南京 210023;南京中医药大学 药学院, 江苏 南京 210023;南京中医药大学 药学院, 江苏 南京 210023;南京中医药大学 药学院, 江苏 南京 210023;江苏省中药高效给药系统工程技术研究中心, 江苏 南京 210023;南京市中药微丸产业化工程技术研究中心, 江苏 南京 210023 |
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| 基金项目： | 国家自然科学基金项目(81073071,81273655);江苏高校优势学科建设工程项目(ysxk-2010);南京中医药大学中药学一级学科开放课题项目(2011ZYX3-007);江苏省2013研究生创新计划项目(CXZZ13-0629) |
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| 摘 要： | 载药微粒是一类应用前景广阔的定向、定位、控释给药系统载体。各种微载体给药系统在促进吸收,提高稳定性,定位、控制释放方面各有优势,如果能结合中药的特点,构建中药有效成分、有效部位、中药复方口服微载体给药系统,对中药新型给药系统的研究具有深远意义。该文主要介绍了几种可用于口服的微载体药物递送系统的特点和优势,并对其在中药领域中的应用进行了综述。
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| 关 键 词： | 微粒 微载体给药系统 口服 中药 |
| 收稿时间： | 2013-05-13 |
Application of oral micro-carrier drug delivery system in studies on traditional Chinese medicine |
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| BI Xiao-lin,LIU Xuan,ZU Qiang and DI Liu-qing. Application of oral micro-carrier drug delivery system in studies on traditional Chinese medicine[J]. China Journal of Chinese Materia Medica, 2013, 38(21): 3638-3644 |
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| Authors: | BI Xiao-lin LIU Xuan ZU Qiang DI Liu-qing |
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| Affiliation: | School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Engineering Research Center for Efficient Delivery System of Traditional Chinese Medicine, Nanjing 210023, China;Nanjing Engineering Research Center for Industrialization Traditional Chinese Medicine Pellets, Nanjing 210023, China;School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China;School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China;School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China;Jiangsu Engineering Research Center for Efficient Delivery System of Traditional Chinese Medicine, Nanjing 210023, China;Nanjing Engineering Research Center for Industrialization Traditional Chinese Medicine Pellets, Nanjing 210023, China |
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| Abstract: | Drug-loading micro-particles are a targeted, positioned and controlled-release drug delivery carrier with a wide application prospect. Various micro-carrier drug delivery systems have their own advantages in promoting absorption, improving stability, targeting and controlled release. Accordingly, it is of far-reaching significance for the studies on micro carrier drug delivery systems to build oral traditional Chinese medicine(TCM) compound micro-carrier drug delivery systems with effective TCM components and effective fractions. This article introduces several features and advantages of oral micro-carrier drug delivery systems, and summarizes their application in the field of TCMs. |
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| Keywords: | micro-particle micro-carrier drug delivery system oral administration traditional Chinese medicine |
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