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Suicidal behavior in schizophrenia and schizoaffective disorder
Institution:1. Department of Neurosciences, Unit of Psychiatry, Sapienza University of Rome, School of Medicine and Psychology, Via di Grottarossa 1035-39, 00198 Rome, Italy;2. Department of Psychiatry and Behavioral Sciences, Emory School of Medicine, Grady Hospital, Atlanta, Georgia;3. Department of Neurosciences, Unit of Neurology, Sapienza University of Rome, School of Medicine and Psychology, Via di Grottarossa 1035-39, 00198 Rome, Italy;1. Research and Development Unit, Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, Barcelona 08830, Spain;2. Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos 3-5 Pabellón 11, Madrid 28029, Spain;3. The Stockholm Centre for Health and Social Change (SCOHOST), Södertörn University, Huddinge 141 89, Sweden
Abstract:Individuals with schizophrenia and schizoaffective disorder are at increased risk for completed suicide and suicide attempts. Suicide risk is increased throughout the life span and most suicide attempters and completers make more than one attempt. Investigations show that individuals with these psychotic disorders are typically experiencing psychotic symptoms and in psychiatric treatment at the time of their attempts although frequently under-treated with respect to medication. We review the literature with regard to demographic and clinical risk factors for suicidal behavior among individuals with schizophrenia and schizoaffective disorder. Specifically the role of clinical symptoms, premorbid and current social functioning, depression, substance misuse and abuse and biological factors are presented. Future directions for research regarding assessment and intervention are discussed.
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