246例子宫平滑肌肿瘤临床病理分析

目的:探讨子宫平滑肌肿瘤临床病理特征.方法:对246例子宫平滑肌肿瘤的临床病理资料进行回顾性分析.结果:子宫平滑肌肿瘤发病高峰年龄为40～50岁,可伴内膜增生或腺肌病,同时与卵巢、宫颈多种良恶性病变并存.246例子宫平滑肌肿瘤中,91.4%为普通型良性平滑肌瘤;6.9%为平滑肌瘤特殊组织学类型;0.8%为平滑肌肉瘤;0...

Uterine smooth muscle tumors:A clinicopathologic analysis of 246 cases

Objective To investigate the clinicopathological features of uterine smooth muscle tumors.Methods Clinical and pathological data from 246 cases of uterine smooth muscle tumors were analyzed retrospectively.Results The peak time for incidence of uterine smooth muscle tumors is in patients with 40 ～ 50 years old.Uterine smooth muscle tumors could co-exist with other diseases such as endometrial hyperplasia,adenomyosis,all kinds of benign or malignant pathological change of cervix and ovary.Among 246 cases,the percentage for usual leiomyoma,special leiomyoma,leiomyosarcoma,and smooth muscle tumor with uncertain malignant potential is 91.4%,6.9%,0.8%,and 0.8%,respectively.Conclusion Uterine smooth muscle tumors is gynecological common tumors.Coagulative(tumor) necrosis,severe nuclear atypia,and high mitotic rate are major criterion for diagnosis of benign and malignant tumors.Multiple clinicopathologic factors should be analyzed to predict biological behavior of uterine smooth muscle tumors.