人参及其复方制剂防治肺病的研究进展

人参Panax ginseng是一种具有多种生理功能的传统药食两用植物,是临床上应用最多的中草药之一,有百草之王之称,其复方制剂如人参补肺汤、参麦注射液等被广泛应用于临床。研究表明人参及其复方制剂具有抗动脉粥样硬化、抗心肌缺血、抗肿瘤、抗肝纤维化等作用。在新冠肺炎爆发后,人参及其复方制剂被大量应用于肺损伤保护的临床及实验研究中,发现其对各种肺部疾病具有较好疗效。人参的主要活性成分是其诸多功效的物质基础,从人参皂苷等多种功效成分对人参及其复方制剂治疗肺病的作用及机制方面进行综述,为人参及其复方制剂在临床上发挥更加广泛的治疗作用及其抗肺病作用的深入研究提供参考。

Research progress of Panax ginseng and its compound preparation on lung diseases

Panax ginseng is a traditional medicinal and edible plant with multiple physiological functions. It is one of the most widely used Chinese herbal medicines in clinic. It is known as the king of herb. Prescriptions containing the Ginseng as their principal ingredient such as Renshenbufei Decoction and Shenmai injection are widely used in traditional Chinese Medicine. In addition, a large number of studies have shown that ginseng and its preparations have pharmacological effects such as anti-atherosclerosis, anti-myocardial ischemia, anti-tumor and anti-liver fibrosis. With the outbreak of novel coronavirus pneumonia, Traditional Chinese Medicine is widely applied in clinical and experimental studies on lung injury protection. It is found that they possess good curative effects on various lung diseases. However, the material basis and mechanism of their prevention and treatment on lung diseases are uncertain. The main active components of ginseng are the material basis of bioactivity of ginseng. The present review summarized the effects and mechanisms of ginseng and its preparations in the treatment of lung diseases via its functional components, which will provide a reference for the further study of ginseng and its preparations in anti-pulmonary disease and clinical treatments.