| 尿卟啉谱分析在卟啉病诊断中的应用 |
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| 引用本文： | 李存保,王美玲,韩利芳,近藤雅雄,周秀娟. 尿卟啉谱分析在卟啉病诊断中的应用[J]. 内蒙古医学院学报, 2003, 25(3): 143-147 |
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| 作者姓名： | 李存保 王美玲 韩利芳 近藤雅雄 周秀娟 |
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| 作者单位： | 1. 内蒙古医学院生物化学教研室,内蒙古,呼和浩特,010059
2. 日本国立公众卫生院营养生物化学部,东京 |
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| 摘 要： | 目的：建立新的卟啉化合物的快速测定法，确定卟啉病诊断用的尿卟啉谱。方法：用反相高效液相色谱法测定卟啉代谢病病人尿液各种卟啉化合物的含量。结果：建立了一套在10min内测定卟啉化合物的方法和卟啉病诊断卟啉谱。结论：该法简便、快速准确度高，为卟啉病的诊断和治疗提供可靠的依据。
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| 关 键 词： | 卟啉 卟啉病 卟啉谱 高效液相色谱法 |
| 文章编号： | 1004-2113(2003)03-0143-05 |
| 修稿时间： | 2003-04-23 |
APPLICATION OF URINARY PORPHYRIN PATTERN ANALYSIS AT DIAGNOSIS OF PORPHYRIA |
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| LI Cun|bao, WANG Mei|ling, HAN Li|fang,et al. APPLICATION OF URINARY PORPHYRIN PATTERN ANALYSIS AT DIAGNOSIS OF PORPHYRIA[J]. Acta Academiae Medicinae Neimongol, 2003, 25(3): 143-147 |
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| Authors: | LI Cun|bao WANG Mei|ling HAN Li|fang et al |
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| Abstract: | Objective: To establish the method of quantitative analysis of porphyrins, and obtain the urinary porphyrin pattern for the diagnosis of porphyria. Methods: The quantitative analysis of urinary porphyrin was evaluated by high performance liquid chromatography(HPLC). Results: The analytical procedure for porphyrins in a sample was completed within 10 min, and the porphyrin patterns for diagnostic system of porphyria was established. Conclusion: This method was found to be simple, quick and high accuracy. To provide the referenced foundation for the diagnosis and treatment of porphyria.; |
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| Keywords: | porphyrin porphyria urinary porphyrin pattern HPLC |
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