原发性高血压患者使用降压药物影响因素Logistic分析

目的：了解降压药物的临床应用情况，探讨降压药物临床用药的特点、选用规律、倾向及合理性。方法：抽取某三甲医院2008年1～11月的第一诊断为原发性高血压住院病历310份，对患者的临床特点、使用降压药物的影响因素进行统计分析。结果：极高危患者最多，占95．16％。大多数患者有合并症。药物使用频率较高的是钙拮抗药，其次是血管紧张素Ⅱ受体阻断药和B-受体阻断药。大部分联合用药，占91．94％。降压药物使用受患者个体状况、药物作用特点、不良反应、相互作用、循证医学证据等多种因素影响。结论：该院降压药物使用注重个体化原则，使用基本合理，与指南相符。

Logistic Analysis of the Utilization of Antihypertensive Drugs for Essential Hypertension Patients

Objective： To investigate antihypertensive drugs utilization in clinic and explore its characteristics, regularity, tendency and rationality. Method ：310 history cases of inpatients with the first diagnosis as essential hypertension were taken in a third-grade A-class hospital from January to November of 2008. Their clinical characteristics, uses and factors were statistically analyzed. Result：The ultra-high-risk patients were the most, accounting for 95.16%. The majority had their complications. The usage frequency of CCB was the highest,next came ARB and the third rank was β-blocks. The drug combination therapy was the majority, accounting for 91.94%. Antihypertensive drugs utilization was affected by such factors as individual, action characters of drug, adverse reaction, drug interaction and evidence of evidence-based medicine. Conclusion：The hospital paid attention to individual management of the utilization of antihypertensive drugs, which was rational and in accordance with their guidelines.