Randomised double blind study of hypotonic oral rehydration
solution in diarrhoea |
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Authors: | T Rautanen S Kurki T Vesikari |
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Institution: | Department of Paediatrics, Jorvi Hospital, Espoo, Finland. |
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Abstract: | Accepted 19 November 1996 A hypotonic (osmolality 224 mmol/l, sodium 60 mmol/l) oral
rehydration solution (ORS) was compared with an isotonic high glucose ORS (osmolality 304 mmol/l, sodium 60 mmol/l) in children with acute
diarrhoea in a randomised double blind study. The stool output and
hence the mean consumption of ORS for maintenance hydration was less (p = 0.036) in patients receiving hypotonic (69 ml/kg) than isotonic (97 ml/kg) ORS. Hypotonic ORS was more effective in patients with rotavirus
positive than with rotavirus negative diarrhoea.
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Keywords: | |
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