长托宁治疗急性有机磷农药中毒的疗效评价

目的 探讨长托宁治疗急性有机磷农药中毒的临床效果.方法 选取我院2008年6月-2011年10月收治的90例急性有机磷农药中毒患者,根据患者治疗方法的不同,将患者分为观察组和对照组,每组45例.对照组患者经阿托品治疗,观察组经长托宁治疗,比较两组患者临床疗效.结果 观察组患者全血胆碱酯酶恢复时间与住院时间少于对照组,差异有统计学意义（P＜0.05）;观察组治愈率100.0%（45/45）高于对照组91.1%（41/45）,差异有统计学意义（P＜0.05）.结论 长托宁可以有效的改善急性有机磷农药中毒患者的病情,缩短患者的住院时间,且安全性较好,适合在临床治疗中推广使用.

Curative Effect Evaluation of Penehyclidine Hydrochloride in the Treatment of Acute Organophosphorus Pesticide Poisoning

Objective To study the clinical effect of penehyclidine hydrochloride in the treatment of acute organophosphorus pesticide poisoning.Methods A total of 90 patients with acute organophosphorus pesticide poisoning in our hospital from June 2008 to October 2011 as the research object.The patients were divided into observation group and control group according to the different treatment methods for the patients,45 cases in each group.Control group：atropine treatment.Observation group：penehyclidine hydrochloride treatment.To compare the clinical effect of the two groups.Results The recovery time of whole blood cholinesterase and hospital stays of observation group were shorter than control group,the difference was statistically significant（P＜0.05）.The cure rate of observation group was 100%（45/45）,which was higher than 91.1%（41/45）of control group,the difference was statistically significant（P＜0.05）.Conclusion Penehyclidine hydrochloride can effectively improve the condition,in patients with acute organophosphorus pesticide poisoning,shorten hospitalization time,and the safety is good,is suitable for use in clinical treatment.