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皮肤母细胞性NK细胞淋巴瘤一例
引用本文:钟华,黄慧,张琬,闫衡,叶庆佾,钟白玉,杨希川.皮肤母细胞性NK细胞淋巴瘤一例[J].国际皮肤性病学杂志,2009,35(6).
作者姓名:钟华  黄慧  张琬  闫衡  叶庆佾  钟白玉  杨希川
作者单位:重庆第三军医大学西南医院皮肤性病科,400038
摘    要:患者男,20岁,因右大腿起皮疹5个月,泛发全身2个月余就诊.体检:躯干、四肢散在分布的蚕豆至鸽蛋大小的暗红色结节,表面无破溃,质韧,无压痛.全身浅表淋巴结未扪及.背部皮损组织病理及免疫组化染色证实为母细胞性NK细胞淋巴瘤.经依托泊苷+环磷酰胺+长春新碱+地塞米松+甲氨蝶呤方案化疗后缓解.

关 键 词:淋巴瘤  杀伤细胞  天然  少见病

Cutaneous blastic NK-cell lymphoma: a case report and literature review
ZHONG Hua,HUANG Hui,ZHANG Wan,YAN Heng,YE Qing-yi,ZHONG Bai-yu,YANG Xi-chuan.Cutaneous blastic NK-cell lymphoma: a case report and literature review[J].International Journal of Dermatology and Venereology,2009,35(6).
Authors:ZHONG Hua  HUANG Hui  ZHANG Wan  YAN Heng  YE Qing-yi  ZHONG Bai-yu  YANG Xi-chuan
Abstract:A 20-year-old man presented with nodules on the right thigh for seven months. Two months prior to the presentation, the lesions spread all over the body. Physical examination revealed dark erythematous, broad bean to pigeon egg-sized, tough, painless nodules without ulceration on the trunk and limbs. Superficial lymph nodes were unpalpable. A diagnosis of blastic NK-cell lymphoma was made based on histopathology and immunohistochemistry. The condition was relieved after chemotherapy with etoposide, cyclophosphamide, vincristine, dexamethasone and methotrexate.
Keywords:Lymphoma  Killer cells  natural  Rare diseases
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