西南地区51家医院2000年～2002年氟喹诺酮类药物应用分析

目的 :了解2000年～2002年氟喹诺酮类药物在西南4省市医院中的应用情况 ,评估其现状和趋势。方法 :对西南4省市51家医院应用氟喹诺酮类药物的品种、用药金额、DDDs等进行统计分析。结果 :2000年～2002年共应用氟喹诺酮类药物13个品种 ;2000年、2001年、2002年的用药金额分别为7391、9342、13242万元 ,年平均增长34.08% ,用药金额上升主要是左氧氟沙星、司帕沙星、氧氟沙星的用量增加所致 ;DDDs2001年、2002年比2000年平均减少17.58 %、19.38 % ,主要是诺氟沙星的用量显著减少所致 ,但每年日平均用药金额无明显差异 ;氧氟沙星、环丙沙星、诺氟沙星和洛美沙星滴眼液、滴鼻液用量较大。结论 :氟喹诺酮类药物在西南地区是一类应用普遍的抗菌药物 ,一些较新的品种如左氧氟沙星和司帕沙星的用量正逐年迅速增长

Analysis of Fluoroquinolone Consumption in 51 Hospitals in Southwest District of China During the Period 2000～2002

OBJECTIVE:To survey and evaluate the present situation and trends o f fluoroquinolones(FQNs) used in hospitals in four provinces,southwest district of China,during the period 2000～2002 METHODS:FQNs used in 51 hospitals in 4 provinces(cities) were analyzed statistically in respect to the sum of money ,main kinds and DDDs etc RESULTS:During the period 2000～2002,a total of 13 kinds of FQNs was used in these hospitals The consumption sums of FQNs in 2000 ,2001 and 2002 were 7 391,9 342 and 13 242 ten-thousand yuans respectively wi th an annual increase rate of 34 08%,of which the main cause was due to the i ncreasing consumption of levofloxacin,sparfloxacin and ofloxacin,however,the DDDs of FQNs in 2001 and 2002 decreased by 17 58% and 19 38% respectively,c ompared with that in 2000,which resulted from the reducing consumption of norfl exacin,but no significant differences were found in the average DDD costs among three years Meanwhile,the nasal drops and eye drops of ofloxacin,ciprofloxac in,norfloxacin and lomefloxacin were consumed a large amount during these three years CONCLUSION:FQN is a kind of commonly-used antimicrobial in southwest d istrict of China And the consumption of some newly-developed FQNs such as levo floxacin and sparfloxacin has increased fast year by year