Dietary fatty acids and insulin resistance |
| |
Authors: | Jennifer C Lovejoy PhD |
| |
Institution: | (1) Women’s Nutrition Research Program, Pennington Biomedical Research Center, 6400 Perkins Road, 70808-4124 Baton Rouge, LA |
| |
Abstract: | High-fat diets have been associated with insulin resistance, a risk factor for both Type II diabetes and heart disease. The
effect of dietary fat on insulin varies depending on the type of fatty acid consumed. Saturated fatty acids have been consistently
associated with insulin resistance. On the other hand, medium and long-chain fatty acid intakes are associated with insulin
sensitivity, as are high intakes of ϕ3 fatty acids. Trans fatty acids appear to potentiate insulin secretion, at least in
the short-term, to a greater degree than cis fatty acids. This may reflect chronic alterations in insulin sensitivity, although
this remains to be tested. In summary, although it must be emphasized that all diets high in fat cause insulin resistance
relative to high-carbohydrate diets, it appears that dietary saturated, short-chain and ϕ6 fatty acids have the most deleterious
effects on insulin action. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|