血管瘤样恶性纤维组织细胞瘤

根据临床和病理学特点以及免疫组织化学方法，观察32例血管瘤样恶性纤维组织细胞瘤，以进一步阐述这一软组织肿瘤的特点和生物学行为。其组织病理学特点为：（1）囊性出血性肿块；（2）瘤细胞似纤维母细胞和组织细胞样细胞；（3）瘤组织内有较多的淋巴细胞为主的慢性炎细胞浸润；（4）瘤周围形成假包膜及淋巴滤泡样结构，易误诊为淋巴结转移性肿瘤。4例做了免疫组织化学，均为溶菌酶阳性，3例Mac387和CD68阳性，支持为组织细胞起源。25例获随访结果者均存活，其中4例复发，1例有转移，显示其为一恶性程度很低的肿瘤，预后明显好于普通型恶性纤维组织细胞瘤。

Angiomatoid malignant fibrous histiocytoma

By clinical, pathologic and immunohistochemical study on aniomatoid malignant fibroushistiocytoma, which is a relatively uncommon soft tissue tumor described by Enzinger in 1979, and of ten misdiagnosed, we are reporting 32 cases of this lesion. The distinctive histopathology were: (1 )Cystic change filled with hemorrhagic fluid or blood, (2) surrounded by nests of fibroblastlike and histi ocyte-like cells and (3) intermingled with chronic inflammatory cells, (4) ofter surrounded by a fibrouspseudocapsule. Immunohistochemical staining done in 4 cases showed all to be posit ive in lysozyme,three positive in Mac 387 and CD 68. These results support their histiocytic origin. Follow-up informa tion was available in 25 of 32 cases. All the 25 patients were alive, 4 with recurrence (16%), 1 withmetastasis (4% ). These results concur with the opinion that intrinsically, this is a low grade tumor.