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Change in Sleep Duration and Type 2 Diabetes: The Whitehall II Study
Authors:Jane E. Ferrie  Mika Kivim?ki  Tasnime N. Akbaraly  Adam Tabak  Jessica Abell  George Davey Smith  Marianna Virtanen  Meena Kumari  Martin J. Shipley
Abstract:OBJECTIVEEvidence suggests that short and long sleep durations are associated with a higher risk of type 2 diabetes. Using successive data waves spanning >20 years, we examined whether a change in sleep duration is associated with incident diabetes.RESULTSCompared with the reference group of persistent 7-h sleepers, an increase of ≥2 h sleep per night was associated with a higher risk of incident diabetes (odds ratio 1.65 [95% CI 1.15, 2.37]) in analyses adjusted for age, sex, employment grade, and ethnic group. This association was partially attenuated by adjustment for BMI and change in weight (1.50 [1.04, 2.16]). An increased risk of incident diabetes was also seen in persistent short sleepers (average ≤5.5 h/night; 1.35 [1.04, 1.76]), but this evidence weakened on adjustment for BMI and change in weight (1.25 [0.96, 1.63]).CONCLUSIONSThis study suggests that individuals whose sleep duration increases are at an increased risk of type 2 diabetes. Greater weight and weight gain in this group partly explain the association.
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