| 天麻注射液,去天麻甙部分和天麻甙药理作用的比较 |
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| 引用本文： | 黄俊华,王桂莲.天麻注射液,去天麻甙部分和天麻甙药理作用的比较[J].中国医学科学院学报,1989,11(2):147-150. |
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| 作者姓名： | 黄俊华 王桂莲 |
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| 作者单位： | 中国医学科学院药物研究所 北京
(黄俊华)，中国医学科学院药物研究所 北京(王桂莲) |
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| 摘 要： | 1985年作者观察到天麻注射液能提高心肌对~86的摄取、减少小鼠的自主活动、与戊巴比妥钠有协同作用,并能提高小鼠的抗缺氧能力;而天麻甙则无以上作用。天麻甙在天麻注射液中含量高达0.45～0.5％,且国内许多药厂在生产合成天麻甙并在临床广为应用。为进一步弄清天麻甙的作用,本实验比较观察天麻注射液、去天麻甙部分和天麻甙的部分药理作用。
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| 关 键 词： | 天麻注射液 天麻甙 天麻甙药作用 |
Comparison studies on pharmacological properties of injectio gastrodia elata, gastrodin-free fraction and gastrodin |
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| J H Huang.Comparison studies on pharmacological properties of injectio gastrodia elata, gastrodin-free fraction and gastrodin[J].Acta Academiae Medicinae Sinicae,1989,11(2):147-150. |
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| Authors: | J H Huang |
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| Abstract: | Injectio Gastrodia elata showed sedative effect on central nervous system with decrease of spontaneous motor activity and a prolonged pentobarbital sleeping time in mice. After administration of injectio Gastrodia, mice were found to be more resistant to hypoxia and nutrient blood flow in cardiac muscle of mice was markedly increased. Besides, It also showed effect of injectio on the croton-oil-induced mouse ear inflammation. The gastrodin-free fraction showed similar but weaker effects as the injectio while no effect was observed of gastrodin in mice. The results show that gastrodin is one of the main constituents of Gastrodia elata, but not the active one. |
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