Immunotherapy of hematologic malignancies and metastatic solid tumors in experimental animals and man |
| |
| Authors: | Slavin S Or R Prighozina T Gurevitch O Aker M Panighari S Shapira M Nagler A |
| |
| Affiliation: | Department of Bone Marrow Transplantation and Cancer Immunotherapy, Hadassah University Hospital, Jerusalem, Israel. |
| |
| Abstract: | Following engraftment of donor hematopoietic cells and induction of host-versus-graft tolerance, immunocompetent lymphocytes of donor origin can induce graft-versus-leukemia (GVL) and graft-versus-tumor (GVT) effects. Engraftment of allogeneic bone marrow cells can be accomplished following non-myeloablative conditioning while possibly controlling graft-versus-host disease (GVHD). GVL and GVT effects may thus be successfully accomplished following non-myeloablative stem cell transplantation (NST) as shown by data derived from experimental animals and man. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
