扩散张量成像在不典型脑膜瘤与星形细胞肿瘤鉴别诊断中的价值

目的探讨扩散张量成像(DTI)鉴别不典型脑膜瘤与星形细胞肿瘤的价值。材料与方法搜集45例经病理证实的脑肿瘤患者(不典型脑膜瘤17例;不同级别星形细胞肿瘤28例),均做了MR DTI,获得FA图和ADC图,分别测量肿瘤实质区、瘤周区与健侧正常脑白质区的平均FA值和ADC值。用统计学软件SPSS19.0分别对不典型脑膜瘤与星形细胞肿瘤两组肿瘤实质区、瘤周区和健侧正常脑白质区FA值和ADC值进行统计学分析,统计结果均以x±s表示,P<0.05为差异有统计学意义。结果不典型脑膜瘤肿瘤实质区、瘤周区、健侧正常脑白质区FA值分别为0.23±0.05、0.20±0.04、0.28±0.04;星形细胞肿瘤上述3个区FA值分别为0.05±0.01、0.14±0.03、0.26±0.04,上述两组肿瘤实质区、瘤周区FA值比较均有显著统计学差异(P值均<0.01),不典型脑膜瘤肿瘤实质区和瘤周区FA值高于星形细胞肿瘤(P<0.05)。不典型脑膜瘤肿瘤实质区、瘤周区、健侧正常脑白质区ADC值分别为(0.82±0.13)、(1.22±0.32)、(0.73±0.10)×10-9mm2/s;星形细胞肿瘤上述3个区ADC值分别为(1.82±0.17)、(1.71±0.10)、(0.70±0.06)×10-9mm2/s。上述两组肿瘤实质区、周区ADC值比较均有显著统计学差异(P值均<0.01)。结论测量肿瘤实质区和瘤周区FA值和ADC值可鉴别不典型脑膜瘤和星形细胞肿瘤。

The value of diffusion tensor MR imaging in differentiating atypical meningioma from glioma

Objective： To observe the value of diffusion tensor MR imaging in differentiating atypical meningioma from glioma.Materials and Methods： Fortyfive patients with pathologically proven brain tumor（17 atypical meningioma,28 different grade gliomas） under went diffusion tensor MR imaging Mean fractional anisotropy（FA） and apparent diffusion coefficient（ADC） values were measured in the tumor parenchyma,peritumoral region and corresponding contralateral normal brain tissue.The FA and ADC in the tumor parenchyma,peritumoral region and corresponding contralateral normal brain tissue of atypical meningioma and glioma were analyzed by SPSS 19.0.The results were expressed as x±s and P0.05 was regarded as statistically significant differences.Results： There were many differences with FA in parenchyma,peritumoral region and corresponding contralateral normal brain tissue between atypical meningioma（0.23±0.05,0.20±0.04,0.28±0.04） from glioma（0.05±0.01,0.14±0.03,0.26±0.04）.There were also many differences with ADC（×10-9mm2/s） in parenchyma,peritumoral region and corresponding contralateral normal brain tissue between atypical meningioma（0.82±0.13,1.22±0.32,0.73±0.10） from glioma（1.82±0.17,1.71±0.10,0.70±0.06）.Conclusions： Measurement of tumor parenchyma and peritumoral region＇s FA values and ADC values can identify atypical meningioma and glioma.