| 膀胱癌患者尿脱落细胞中人巨细胞病毒的定量分析 |
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| 引用本文： | 秦逸秋 张云英 等. 膀胱癌患者尿脱落细胞中人巨细胞病毒的定量分析[J]. 环境与职业医学, 2001, 18(3): 151-153 |
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| 作者姓名： | 秦逸秋 张云英 等 |
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| 作者单位： | [1]上海市疾病预防控制中心职业卫生科，上海200036 [2]农科院寄生虫病研究所，上海200232 |
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| 基金项目： | 该文获中华医学会上海分会施思明基金奖。 |
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| 摘 要： | 目的：初步探讨人巨细胞病毒感染与膀胱癌的关系。方法：采用一种新的PCR产物定量测定技术，对12例膀胱癌病人，24例健康人的尿脱落细胞病理标本进行人巨细胞病毒（HCMV）的定量检测，并结合临床资料，探讨膀胱癌与HCMV感染的关系。结果：12例膀胱癌病人中有8例阳性，24例对照人群中无阳性发现，表明膀胱癌细胞内存在有HCMV基因的DNA。结论：膀胱癌病人中有较高的HCMV感染，并可能在膀胱癌的发生和发展中起着重要作用。
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| 关 键 词： | 膀胱癌 人巨细胞病毒 定量PCR 脱落细胞 |
| 文章编号： | 1006-3617(2001)02-0151-03 |
| 修稿时间： | 2001-01-03 |
Quantitative Analysis on Human Cytomegalovirus (HCMV) of Exfoliated Cells in Urine from Bladder Cancer |
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| QIN Yi qiu ,ZHANG Yun ying ,SHEN Hong ,WANG Wen jing ,ZHONG Shu mei ,LI Yan hong ,RUAN Su yun. Quantitative Analysis on Human Cytomegalovirus (HCMV) of Exfoliated Cells in Urine from Bladder Cancer[J]. Journal of Environmental & Occupational Medicine, 2001, 18(3): 151-153 |
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| Authors: | QIN Yi qiu ZHANG Yun ying SHEN Hong WANG Wen jing ZHONG Shu mei LI Yan hong RUAN Su yun |
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| Affiliation: | QIN Yi qiu 1,ZHANG Yun ying 1,SHEN Hong 1,WANG Wen jing 1,ZHONG Shu mei 2,LI Yan hong 1,RUAN Su yun 1 |
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| Abstract: | Objective] To explore the relationship between the infection of human cytomegalovirus (HCMV) and bladder cancer. [Methods] Specimens of exfoliated cells in urine from 12 bladder cancer patients and 24 health controls have been studied by quantitative polymerase chain reaction (PCR). [Results] The human cytomegalovirus (HCMV) DNA was detected in exfoliated cells in urine from 8 bladder cancer patients of 12,while not in controls. [Conclusion] The infectious rate of ACMV in bladder cancer patients is high. HCMV might play an important role in the occurrence and development of bladder cancer. |
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| Keywords: | bladder cancer human cytomegalovirus(HCMV) quantitative PCR exfoliated cell |
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