Use of hypertonic saline in the treatment of cerebral edema in diabetic ketoacidosis (DKA) |
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Authors: | Curtis J R Bohn D Daneman D |
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Affiliation: | Department of Pediatrics, Division of Endocrinology and the;Division of Critical Care, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada |
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Abstract: | Abstract: Cerebral edema is the primary cause of morbidity and mortality in children and adolescents with diabetic ketoacidosis (DKA). We report a case of an adolescent female with life-threatening DKA-related cerebral edema who responded to a combination of mannitol and hypertonic saline. This is the first report of the use of hypertonic saline in the treatment of cerebral edema due to DKA. |
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Keywords: | brain edema diabetic ketoacidosis hypertonic saline solution |
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