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Use of hypertonic saline in the treatment of cerebral edema in diabetic ketoacidosis (DKA)
Authors:Curtis J R  Bohn D  Daneman D
Affiliation:Department of Pediatrics, Division of Endocrinology and the;Division of Critical Care, The Hospital for Sick Children, The University of Toronto, Toronto, Ontario, Canada
Abstract:Abstract: Cerebral edema is the primary cause of morbidity and mortality in children and adolescents with diabetic ketoacidosis (DKA). We report a case of an adolescent female with life-threatening DKA-related cerebral edema who responded to a combination of mannitol and hypertonic saline. This is the first report of the use of hypertonic saline in the treatment of cerebral edema due to DKA.
Keywords:brain edema    diabetic ketoacidosis    hypertonic    saline solution
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