Successful challenge with the fully human EGFR antibody panitumumab following an infusion reaction with the chimeric EGFR antibody cetuximab. |
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| Authors: | D Helbling M Borner |
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| Affiliation: | Department of Medical Oncology, Clinic of Medical Oncology, University Hospital Inselpital Bern, Freiburgstrasse, 3010 Bern, Switzerland |
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| Abstract: | Infusion reactions are serious complications associated withmodern antibody therapy. In order to reduce the incidence andseverity of such reactions, the newer generations of monoclonalantibodies contain less or no mouse-specific protein sequences.We describe the clinical course of a patient who experiencedan infusion |
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