| �뾭Ƥ��ҩϵͳ���䴴������ҩ��ѧ�о���չ |
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| 引用本文： | �����,�ǽ���,������,��ѡ��. �뾭Ƥ��ҩϵͳ���䴴������ҩ��ѧ�о���չ[J]. 中国药学杂志, 2017, 52(6): 434-437. DOI: 10.11669/cpj.2017.06.002 |
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| 作者姓名： | ����� �ǽ��� ������ ��ѡ�� |
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| 作者单位： | ??????????????????????,???? 730030 |
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| 摘 要： |
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| 关 键 词： | ?????? ?????????? ??? ???????? |
Microneedle Percutaneous Drug Delivery System,Wound Repair and Pharmacology Evaluation |
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| MENG Li-juan,QIAO Jian-xiong,LIN Pei-ting,ZHANG Xuan-fen. Microneedle Percutaneous Drug Delivery System,Wound Repair and Pharmacology Evaluation[J]. Chinese Pharmaceutical Journal, 2017, 52(6): 434-437. DOI: 10.11669/cpj.2017.06.002 |
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| Authors: | MENG Li-juan QIAO Jian-xiong LIN Pei-ting ZHANG Xuan-fen |
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| Affiliation: | Plastic and Aesthetic Surgery, Lanzhou University Second Hospital, Lanzhou 730030, China |
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| Abstract: | ??Transdermal drug delivery offers a number of advantages including improved patient compliance, sustained release, avoidance of gastric irritation, as well as elimination of pre-systemic first-pass effect. However, the skin barrier function limits the transdermal penetration of macromolecular drugs.Microneedle arrays can remarkably increase the skin permeability for drugs, especially macromolecular drugs, by forming microchannels in the skin. In recent years, the types and usages of microneedle have made great progress. This review focuses on remarking the wound repair and pharmacology evaluation, as well as introduces the microneedle percutaneous drug delivery system. |
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