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Improved prediction of HLA antigen presentation hotspots: Applications for immunogenicity risk assessment of therapeutic proteins |
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| Authors: | Anders Steenholdt Attermann Carolina Barra Birkir Reynisson Heidi Schiler Schultz Ulrike Leurs Kasper Lamberth Morten Nielsen |
| Institution: | 1. Department of Health Technology, Technical University of Denmark, Lyngby Denmark ; 2. Assay, Analysis & Characterisation, Global Research Technologies, Novo Nordisk A/S, Måløv Denmark ; 3. Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, Buenos Aires Argentina |
| Abstract: | |
| Keywords: | HLA antigen presentation HLA eluted ligands immunogenicity assessment prediction protein immunogenicity |