| 非胰岛素依赖型糖尿病患者红细胞膜ATP酶活力和细胞内离子水平变化 |
| |
| 引用本文： | 顾明君,殷仁富,刘志民,仇韶华.非胰岛素依赖型糖尿病患者红细胞膜ATP酶活力和细胞内离子水平变化[J].上海医学,1993(6). |
| |
| 作者姓名： | 顾明君 殷仁富 刘志民 仇韶华 |
| |
| 作者单位： | 第二军医大学附属长征医院内分泌科，第二军医大学附属长征医院内分泌科，第二军医大学附属长征医院内分泌科，第二军医大学附属长征医院内分泌科 |
| |
| 摘 要： | 测定20例正常人及40例 NIDDM 患者红细胞膜 ATP 酶活力和红细胞内离子浓度。结果NIDDM 患者 Na~+-K~+-ATP 酶、Ca~(2+)-ATP 酶活力明显低于正常人(P 均<0.001),Mg~(2+)-ATT 酶活力无明显改变(P>0.05);NIDDM 患者红细胞内Na~+]、Ca~(2+)]明显高于正常人(P 分别<0.001和0.01),Mg~(2+)]明显低于正常人(P<0.001),K~+]无明显变化(P>0.05)。上述变化在无血管病者就已出现,有血管病者更加明显。
|
| 关 键 词： | 非肤岛素依赖型糖尿病 三磷酸腺苷酶 阳离子浓度 |
CHANGES OF ATPase ACTIVITY OF ERYTHROCYTIC MEMBRANE AND INTRA-ERYTHROCYTIC IONIC LEVELS IN NON INSULIN-DEPENDENT DIABETES MELLITUS(NIDDM) PATIENTS |
| |
| Gu Min-jun et al Changzhen Hospital,The Second Military Medical University,Shanghai.CHANGES OF ATPase ACTIVITY OF ERYTHROCYTIC MEMBRANE AND INTRA-ERYTHROCYTIC IONIC LEVELS IN NON INSULIN-DEPENDENT DIABETES MELLITUS(NIDDM) PATIENTS[J].Shanghai Medical Journal,1993(6). |
| |
| Authors: | Gu Min-jun Changzhen Hospital The Second Military Medical University Shanghai |
| |
| Institution: | Gu Min-jun et al Changzhen Hospital,The Second Military Medical University,Shanghai,200433 |
| |
| Abstract: | The ATPase activity of erythrocytic membrane and intraerythrocytic ionic levelswere determined in 40 NIDDM patients and 20 healthy controls.The activities of Na~+-K~+-ATPase and Ca~(2+)-ATP ase were significantly lower in diabetics than in controls(P<0.01),and there was no diffence in Mg~(2+)-ATPase activity between the two groups(P>0.05).IntraerythrocyticNa~+]andCa~(2+)]were significantly higher andMg~(2+)] was significantly lower in diabetics than those in controls(P<0.001,0.01 and0.001,respectively),and there was no difference in K~+]between the two groups(P>0.05).These abnormal ties of ATPase activity and ionic levels in NIDDM patientswith vascular lesion were more obvious than these of patients without vascular lesions. |
| |
| Keywords: | NIDDM ATPase activity Cation level |
| 本文献已被 CNKI 等数据库收录！ |
