| HPLC测定抗敏鼻炎灵胶囊中麻黄碱的含量 |
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| 引用本文： | 钟晓明,张静娇,潘爱娟,冯春荣,黄真.HPLC测定抗敏鼻炎灵胶囊中麻黄碱的含量[J].浙江中医药大学学报,2010,34(1):89-90. |
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| 作者姓名： | 钟晓明 张静娇 潘爱娟 冯春荣 黄真 |
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| 作者单位： | 浙江中医药大学药学院,杭州,310053 |
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| 基金项目： | 浙江省科技厅重点项目(No:2005C23011);;浙江省自然基金项目(No:M303771);;浙江省卫生高层次创新人才培养工程项目~~ |
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| 摘 要： | 目的]建立抗敏鼻炎灵中麻黄碱含量测定HPLC方法。方法]色谱条件:色谱柱:DiamonsilTM(钻石)C18(250mm×4.6mm,5μm);流动相为乙腈-0.02mol/L磷酸二氢--钾溶液(含0.2%三乙胺,用磷酸调PH值至2.7)=(5∶95),流速为1.0ml/min,检测波长为210nm,柱温30℃。结果]盐酸麻黄碱线性范围0.2148~2.148μg/ml,r=0.9999;平均回收率为98.85%,RSD=2.95%。结论]该方法简便,准确,重现性好,可作为测定抗敏鼻炎灵中麻黄碱含量的方法。
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| 关 键 词： | 抗敏鼻炎灵胶囊 盐酸麻黄碱 HPLC |
Determination of Saikosaponind in Suyu Dropping Pills by HPLC |
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| Zhong Xiaoming,Zhang Jingjiao,Pan Aijuan,et al Zhejiang University of Traditional Chinese Medicine,Hangzhou.Determination of Saikosaponind in Suyu Dropping Pills by HPLC[J].Journal of Zhejiang University of Traditional Chinese Medicine,2010,34(1):89-90. |
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| Authors: | Zhong Xiaoming Zhang Jingjiao Pan Aijuan Zhejiang University of Traditional Chinese Medicine Hangzhou |
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| Abstract: | Objective] To establish a method for determination of Ephedrine Hydrochloride in KMBYL capsules by HPLC.Methods] The DiamonsilTM C18（250mm×4.6mm,5 μm）column was used.The mobile phase was mobile phase： acetonitrine-0.02 mol·L-1potassium dihydrogen phosphate（0.2% triethylamine,adjusteding pH to 2.7 with phosphoric acid）（5∶95） with a flow rate of 1.0ml·min-1.The detection wavelength was 210 nm.The column temperature was 30℃.Results] The linear responses range was 0.2148-2.148 μg？mL-1 of Ephedrine Hydrochloride（r=0·9999）.The average recovery was 98.85% and the RSD was 2.95%.Conclusion] The method is simple accurate reproducible.It can be used for the quality control of KMBYL Capsules. |
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| Keywords: | KMBYL Capsules Ephedrine 'HPLC' |
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