Development of insulin-dependent diabetes mellitus during the hemolytic-uremic syndrome |
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Authors: | S P Andreoli J M Bergstein |
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Affiliation: | Department of Pediatrics, Indiana University School of Medicine. Indianapolis, Ind. USA |
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Abstract: | Three children developed hyperglycemia and ketoacidosis three, eight, and 60 days after the onset of hemolytic-uremic syndrome. During hyperglycemia, the two patients studied had dramatically low insulin concentrations. Circulating islet-cell and insulin antibodies were not detected. These studies suggest that pancreatic beta cell dysfunction may occur during hemolytic-uremic syndrome, and that the serum glucose concentration should be closely monitored during this disease. |
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Keywords: | Reprint address: James Whitcomb Riley Hospital for Children 1100 West Michigan St. Indianapolis IN 46223. |
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