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包头地区乳腺肿瘤及其复发转移的血清微量元素变化研究
引用本文:李晓凤,段爱文,李佳,刘爱勇,赵欣.包头地区乳腺肿瘤及其复发转移的血清微量元素变化研究[J].癌症进展,2008,6(6):641-644.
作者姓名:李晓凤  段爱文  李佳  刘爱勇  赵欣
作者单位:包头市肿瘤医院内二科,包头,014030;包头市肿瘤医院内二科,包头,014030;包头市肿瘤医院内二科,包头,014030;包头市肿瘤医院内二科,包头,014030;包头市肿瘤医院内二科,包头,014030
摘    要:目的探讨9种微量元素与乳腺肿瘤的关系。方法采用原子吸收分光度计对81例健康女性志愿者、94例乳腺良性肿瘤患者、93例乳腺癌患者手术前后和38例乳腺癌复发转移患者血清中Fe、Zn、CU、Mn、Pb、Cd、Cr、Ni、Mo的含量进行测定。结果血清Fe、Zn、Cu、Mn、Pb随乳腺肿瘤病情加重呈明显升高趋势,与乳腺癌呈正相关,而Mo随病情的加重明显降低,与乳腺癌呈负相关。结论有6种微量元素与乳腺肿瘤的发病有显著关系,其中Fe、Zn、Cu、Mn、Pb可能是乳腺癌的危险因素,而Mo为乳腺癌的保护因素。

关 键 词:乳腺肿瘤  血清  微量元素

Study of trace elements in serm of patient breast tumor for its concents changes in breast cancer,breast benign tumor and recurred breast cancer in Baotou area
Li Xiaofeng,Duan Aiwen,Li Jia,Liu Aiyong,Zhao Xin.Study of trace elements in serm of patient breast tumor for its concents changes in breast cancer,breast benign tumor and recurred breast cancer in Baotou area[J].Oncology Progress,2008,6(6):641-644.
Authors:Li Xiaofeng  Duan Aiwen  Li Jia  Liu Aiyong  Zhao Xin
Institution:(Department of Internal Medicine, the Seventh Hosbital of Baotou, Baotou 014030, China)
Abstract:Objective To study the relationship between nine trace elements and breast tumors. Methods The serum levelsofninetraceelements (Fe, Zn, Cu, Mn, Pb, Cd, Cr, Ni, and Mo) in81 healthy women, 94 patients with breast begin tumor, 93 patients with breast cancer, and 38 patients with re' curred breast cancer were measured. Result Along with the increase of the severity of breast tumors, the serum levels of five trace elements (Fe, Zn, Cu, Mn, and Pb) increased, while the level of Mo decreased. Conclution Six elements are correlated with breast tumors. Fe, Zn, Cu, Mn, and Ni may be the risk factors, and Mo is a protective factor.
Keywords:breast tumor  serum trace element
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