依达拉奉治疗急性脑梗死及对神经功能缺损和日常生活能力的疗效

目的 评价依达拉奉治疗急性脑梗死临床疗效及对神经功能缺损和日常生活能力的影响.方法 选择我院2008-07-2011-12收治的急性脑梗死患者80例为对照组,采用常规方法治疗.另选择同期收治的80例急性脑梗死患者为观察组,在常规治疗的同时加用依达拉奉治疗.对比2组的临床疗效及治疗前后神经功能缺损和日常生活能力的变化情况.结果2组经治疗后观察组总有效率为95.00％,对照组为78.75％,2组比较差异有统计学意义(P＜0.05).而治疗后2组神经功能缺损评分均比治疗前显著下降(P＜0.05)而观察组下降更为显著;治疗后2组日常生活能力评分均较治疗前上升,观察组优于对照组(P＜0.05).2组治疗后比较差异有统计学意义(P＜0.05).结论 依达拉奉治疗急性脑梗死临床疗效显著,能明显改善患者的神经功能障碍,提高日常生活自理能力,从而使患者的生活质量得到改善.

Clinical efficacy of in Edaravone in treatment of acute cerebral infarction on neurological impairment and activities of daily living

Objective To evaluate clinical efficacy of Edaravone in the treatment of acute cerebral infarction and edaravone on neurological impairment and activities of daily living.Methods Totally 80 cases of acute cerebral infarction admitted to hospital July 2008 to December 2011 as the control group using conventional methods for treatment.Another selected the same period 80 cases were admitted with acute cerebral infarction 80 cases as the observation group,while in the conventional treatment plus edaravone treatment.Clinical efficacy before and after treatment,neurological deficits and activities of daily living,changes in the two groups were compared.Results After treatment,the total effective rate was 95.00% in observation group,78.75% in the control group,the difference was statistically significant(P<0.05).After treatment,the nerve function defect score decreased significantly than before(P<0.05),while the observation group decreased more significantly;Activities of daily living scores after treatment compared witht before the treatmen were obviously increase,the observation group was better than the control group(P<0.05).After treatment,the difference was statistically significant(P<0.05).Conclusion The clinical efficacy of edaravone in treatment of acute cerebral infarction can significantly improve the neurological dysfunction in patients and improve the daily living skills,so that the patient’s quality of life were improved.