| N端脑钠肽前体对心源性呼吸困难和肺源性呼吸困难鉴别诊断的临床价值研究 |
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| 引用本文： | 汤松涛,朱庆雄,梁桥安. N端脑钠肽前体对心源性呼吸困难和肺源性呼吸困难鉴别诊断的临床价值研究[J]. 齐齐哈尔医学院学报, 2011, 32(12): 1891-1893 |
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| 作者姓名： | 汤松涛 朱庆雄 梁桥安 |
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| 作者单位： | 东莞市寮步医院,广东,523400 |
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| 基金项目： | 2008年东莞市医疗卫生单位科技项目经费资助 |
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| 摘 要： | 目的探讨N端脑钠肽前体（NT-proBNP）在心源性呼吸困难和肺源性呼吸困难诊断鉴别中的应用价值。方法回顾性分析入院治疗的124呼吸困难患者,包括心源性呼吸困难患者61例、肺源性呼吸困难患者63例,均应用罗氏心脏生物标志仪,检测两种呼吸困难患者静脉血NT-proBNP的浓度。结果心源性呼吸困难组患者NT-proBNP浓度明显高于非心源性呼吸困难组患者（P〈0.001）;心源性呼吸困难组NT-proBNP浓度在心功能不同级别间有统计学（P〈0.001）。结论 NT-proBNP简便快捷、敏感性和特异性高,可作为鉴别急性呼吸困难患者的一个观察指标。心源性呼吸困难患者血清NT-proBNP水平明显较肺源性呼吸困难患者高。
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| 关 键 词： | N端脑钠肽前体 心源性呼吸困难 肺源性呼吸困难 |
Clinic value of NT-proBNP in differential diagnosis of cardiac dyspnea and pulmonary dyspnea |
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| Affiliation: | TANG Song-tao,et al.(Liaobu Hospital,Dongguan,Guangdong 523400,the P.R.China.) |
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| Abstract: | Objective To discuss the value of NT-proBNP in differential diagnosis of cardiac dyspnea and pulmonary dyspnea.Methods A retrospective analysis was conducted among 124 hospitalized patients with dyspnea,including 61 patients with cardiac dypnea and 63 patients with pulmonary dyspnea.All patients＇ concentration of NT-proBNP was all measured with Roche cardiac biomarkers.Results The concentrations of NT-proBNP in patients with cardiac dyspnea were significant higher than that of non-cardiac dyspnea（P0.001）,the concentration of NT-proBNP in patients with cardiac dyspnea were significant different among different levels of heart function（P0.001）.Conclusions NT-proBNP can be used as a indicator in differential diagnosis of acute dyspnea because its convenience,highly sensitivity and specificity.The concentrations of NT-proBNP in patients with cardiac dyspnea are significant higher than that of pulmonary dyspnea. |
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| Keywords: | NT-proBNP Cardiac dyspnea Pulmonary dyspnea |
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