儿童卡波希肉瘤与HIV等相关病毒感染

为提高对小儿卡波希肉瘤 (Kaposisarcoma,KS)的认识 ,对 1 4例非洲小儿KS的临床资料、HIV抗体检测结果和组织病理学结果进行分析。结果 :1 4例患儿活组织病理学观察均符合KS诊断 ,其中 1 2例 ( 85 .71 % )HIV抗体阳性。HIV抗体阳性的患儿中 ,婴幼儿组 ( 6月～ 3岁 ) 5例 ( 4 1 .7% ) ,4～ 6岁 1例 ( 8.3% ) ,7～ 9岁 3例 ( 2 5 .0 % ) ,1 0～ 1 4岁 3例 ( 2 5 .0 % ) ;淋巴结型KS占 75 % ,皮肤型占 2 5 %。提示 :小儿HIV感染相关型KS并不少见 ,以婴幼儿组发病率最高 ,以淋巴结型KS为主要临床表现类型 ;应提高对本病的认识 ,及时诊断患儿。

Children with Kaposi Sarcoma Associated with HIV and Other Viruses Infection

The purpose of this research is study the clinical manifestation and classification of Kaposi sarcoma in Africa children, and to analyze the incidence of Kaposi sarcoma associated with HIV infection in pediatric patients. Clinical data of 14 cases were collected. All cases received histopathologic examination, and 14 cases accepted HIV antibody test. Histopathologic examination to 14 cases conformed to the diagnosis of KS and 12 out of 14 tested cases were HIV positive. Among 12 HIV positive cases, the 6-months-to-3-years group accounted for 41.7%. Other three groups accounted for 8.3 %, 25.0%, 25.0% respectively. For the 12 HIV positive cases, lymphatic KS was the main clinical type and occupied 75%. The incidence of pediatric KS associated with HIV infection was not uncommon. Among 12 HIV positive cases, the incidence of the 6-months-to-3-years group was much higher than the other three groups; lymphatic KS was the main clinical type. The result also suggests the possibility of canceration of HIV lymphadenopathy. The delayed diagnosis for most cases requests more attention to this particular problem.