16层CTA与DSA诊断颅内动脉瘤效能的对比研究

目的 对比CTA与DSA诊断颅内动脉瘤的效能.方法 首都医科大学附属北京天坛医院神经外科自2007年7月至2008年7月连续收治疑动脉瘤患者82例,均行DSA与CTA检查,确诊为动脉瘤患者行手术治疗.比较DSA、CTA检查的阳性率和二者诊断动脉瘤的特异性、敏感性和准确性.比较CTA检查与术中测量瘤体、瘤颈直径的大小,观察CTA、DSA检查对不同部位、大小动脉瘤的显示情况.结果 CTA检出动脉瘤74个,DSA正确检出81个,二者阳性率差异无统计学意义(x2=1.897,P=0.163).以DSA检查结果为标准,CTA发现动脉瘤的灵敏性为91.4%(74/81),特异性为91.7%(11/12),准确性为91.4%(85/93);65例患者行手术治疗,术中发现动脉瘤73个,以手术结果为标准,CTA、DSA检查的灵敏性比较差异有统计学意义(P<0.05),特异性、准确性比较差异无统计学意义(P>0.05);与术中测量的瘤体、瘤颈直径比较,CTA检查结果较大,差异有统计学意义(P<0.05);CTA检查对不同部位、大小动脉瘤的灵敏度不同,而DSA检查具有较高敏感性.结论 16层CTA具有无创、快捷、敏感、高效等优点,可做为筛选动脉瘤的方法,部分患者可凭CTA指导手术.

Abstract：

Objective To assess the values of 16-slice CTA and DSA in the diagnosis of intracranial aneurysms. Methods Eighty-two patients with SAH,suspected having aneurysms and admitted to our hospital from July 2007 to July 2008,received DSA and CTA;the clinical data of these patients were analyzed;CTA images were compared blindly with the DSA findings,including the presence,location,and size of aneurysms.With SPSS 11.5 statistical software,the sensitivity,specificity and accuracy of CTA and DSA were compared. Results Eighty-one aneurysms were detected by DSA and 74 aneurysms by CTA;no significant difirences on the positive detected rate were noted(x2=1.897,P=0.163).The sensitivity of CTA for detection of all aneurysms versus that of DSA was 91.4%,the specificity of CTA 91.7%.and the accuracy of CTA 91.4%.Sixty-five patients underwent surgery (clipping)and 73 aneurysms were confirmed by this surgery;CTA had a sensitivity of 89.0%,specificity of 100%and accuracy of 90.5%:DSA had a sensitivity of 98.6%,specificity of 84.6%and accuracy of 98.8%;significant statistical diference on sensitivity (x2=5.625,P<0.05)and no significant statistical diference on specificity and accuracy (x2=1.846 and 2.450,respetively,P>0.05)were found between them.As compared with the sizes of aneurysms and the diameters of aneurysm necks measured during the operation,these results detected by CTA were significantly larger(P<0.05).CTA had different detection sensitivities to aneurysms at different locations and with different sizes,while DSA had high sensitivity.Conclusion CTA is a noninvasive, quick, sensitive and efficient tool to diagnose inrtacranial aneurysms.It can be specially used to screen aneurysms in SAH patients.In some cases,CTA can guide the surgery.

Values of 16-slice CTA and DSA in diagnosis of intracranial aneurysm

Objective To assess the values of 16-slice CTA and DSA in the diagnosis of intracranial aneurysms. Methods Eighty-two patients with SAH,suspected having aneurysms and admitted to our hospital from July 2007 to July 2008,received DSA and CTA;the clinical data of these patients were analyzed;CTA images were compared blindly with the DSA findings,including the presence,location,and size of aneurysms.With SPSS 11.5 statistical software,the sensitivity,specificity and accuracy of CTA and DSA were compared. Results Eighty-one aneurysms were detected by DSA and 74 aneurysms by CTA;no significant difirences on the positive detected rate were noted(x2=1.897,P=0.163).The sensitivity of CTA for detection of all aneurysms versus that of DSA was 91.4%,the specificity of CTA 91.7%.and the accuracy of CTA 91.4%.Sixty-five patients underwent surgery (clipping)and 73 aneurysms were confirmed by this surgery;CTA had a sensitivity of 89.0%,specificity of 100%and accuracy of 90.5%:DSA had a sensitivity of 98.6%,specificity of 84.6%and accuracy of 98.8%;significant statistical diference on sensitivity (x2=5.625,P<0.05)and no significant statistical diference on specificity and accuracy (x2=1.846 and 2.450,respetively,P>0.05)were found between them.As compared with the sizes of aneurysms and the diameters of aneurysm necks measured during the operation,these results detected by CTA were significantly larger(P<0.05).CTA had different detection sensitivities to aneurysms at different locations and with different sizes,while DSA had high sensitivity.Conclusion CTA is a noninvasive, quick, sensitive and efficient tool to diagnose inrtacranial aneurysms.It can be specially used to screen aneurysms in SAH patients.In some cases,CTA can guide the surgery.