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中药骨松康治疗绝经后骨质疏松症临床疗效观察
引用本文:王长海 王文 李军昌 蒋永培 李锋 陈学富 苏世银 林天幕 冯文 石少平. 中药骨松康治疗绝经后骨质疏松症临床疗效观察[J]. 中国骨质疏松杂志, 2003, 9(2): 165-166,131
作者姓名:王长海 王文 李军昌 蒋永培 李锋 陈学富 苏世银 林天幕 冯文 石少平
作者单位:1. 710032,西安,第四军医大学西京医院中医科
2. 710032,西安,第四军医大学西京医院药剂科
摘    要:目的 探讨阴阳双补兼活血化瘀中药对绝经后骨质疏松症 (postmenopausalosteoporosis,PMO)的治疗作用及其机理。方法 按照中药新药临床研究指导原则 ,采用空白对照和前后自身对照的方法 ,观察患者服用骨松康胶囊 (GSKC)前后的主要症状变化及骨密度 (BMD)改变 ,并与西药对照组进行对比。结果 骨松康胶囊对骨质疏松治疗作用显著 (P <0 0 1 ) ,患者骨密度亦有明显改善 (P<0 0 5) ,而对照组则无明显变化。结论 中药骨松康胶囊治疗PMO疗效可靠 ,无明显毒副作用

关 键 词:中药 骨松康胶囊 治疗 绝经 骨质疏松症 PMO 骨密度 BMD

Clinical efficacy of Gusongkang capsule in treatment of postmenopausal osteoporosis
WANG Changhai,WANG Wen,LI Junchang,et al Depar tment of Traditional Chinese Medicine,Xijing Hospital,The Fourth Military Medical University,Xi an ,China. Clinical efficacy of Gusongkang capsule in treatment of postmenopausal osteoporosis[J]. Chinese Journal of Osteoporosis, 2003, 9(2): 165-166,131
Authors:WANG Changhai  WANG Wen  LI Junchang  et al Depar tment of Traditional Chinese Medicine  Xijing Hospital  The Fourth Military Medical University  Xi an   China
Affiliation:WANG Changhai,WANG Wen,LI Junchang,et al Depar tment of Traditional Chinese Medicine,Xijing Hospital,The Fourth Military Medical University,Xi 1an 710032,China
Abstract:Objective To study the effect and mechanism of G usongkang (GSK) capsule, as a yin-yang-tonifying and blood-flow promoting tra ditional chinese medicine, on postmenopausal osteoporosis Methods According to the Guiding Principles for Clinical Study of Traditional Chine se Medicinnal Herbs, the changes of symptoms, signs and bone density in osteopo r osis patients were observed and compared between these indices before-and after therapy with GSK and between groups of GSK and of calcium lactate as control Results GSK improved the osteoporosis patients' symptom (P < 0 01 vs control),and elevated BMD (P<0 05 vs before therapy) Concl usion GSK can remove patients' discomfort from osteoporosis and improve BMD GSK can treat osteoporosis with none of side effects
Keywords:Postmenopausal osteoporosis  Treatment  Traditio nal Chinese herbal medicine  Gusongkong capsule
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