| 氧化应激与高血压研究进展 |
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| 引用本文： | 王佐广,温绍君,吴兆苏. 氧化应激与高血压研究进展[J]. 心血管病学进展, 2009, 30(4): 581-584 |
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| 作者姓名： | 王佐广 温绍君 吴兆苏 |
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| 作者单位： | 首都医科大学附属北京安贞医院,北京市心肺血管疾病研究所,高血压研究室,北京,100029 |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | 原发性高血压的发病机制目前还不完全清楚，但是大量的研究均发现氧化应激在高血压的发病机制和并发症中具有重要的作用。现从基础与临床两个方面，对高血压与氧化应激的相关性、抗高血压药物治疗与氧化应激、抗氧化应激药物与高血压的发病机制、高血压与氧化应激的因果关系等方面对高血压与氧化应激进行了较为系统的阐述，并对一些，临床研究的结果进行了初步评价。最后，对高血压与氧化应激的下一步研究方向和方法进行了展望。
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| 关 键 词： | 氧化应激 高血压 药物治疗 因果关系 |
Progress in Study of Relationship Between Oxidative Stress and Hypertension |
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| WANG Zuog-uang,WEN Shao-jun,WU Zhao-su. Progress in Study of Relationship Between Oxidative Stress and Hypertension[J]. Advances in Cardiovascular Diseases, 2009, 30(4): 581-584 |
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| Authors: | WANG Zuog-uang WEN Shao-jun WU Zhao-su |
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| Affiliation: | WANG Zuo-guang, WEN Shao-jun, WU Zhao-su ( Department of Hypertension, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing Anzhen Hospital Affiliated to Capital University of Medical Sciences, Beijing 100029, China) |
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| Abstract: | The pathogenesis of essential hypertension is not well understood. However, many studies have supported that reactive oxygen species plays a very important role in the mechanism of essential hypertension. In this paper, hasally and clinically, we have reviewed the relationship of hypertension and reactive oxygen species, antihypertensive treatment effect and reactive oxygen species, antioxidative treatment effect and pathogenesis of hypertension, cause and effect relationship of reactive oxygen species and hypertension in detail. |
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| Keywords: | oxidative stress hypertension drug treatment cause and effect |
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