| 诊断儿童病毒性心肌炎的血清抗体联合判别方程及其价值研究 |
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| 引用本文： | 欧阳范献,吴建民,林修寿,卜平凤,谢梅芝,余孝良.诊断儿童病毒性心肌炎的血清抗体联合判别方程及其价值研究[J].中南大学学报(医学版),1996(6). |
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| 作者姓名： | 欧阳范献 吴建民 林修寿 卜平凤 谢梅芝 余孝良 |
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| 作者单位： | Ouyang Fanxian(Clinical Laboratory，The Third Affiliated Hospital，Hunan Medical University)Wu Jianmin(Department of Epidemiology，Hunan Medical University)Yu Xiaoliang(Department of pediatricsy，The Second Affiliated Hospital，Hunan Medical University) |
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| 摘 要： | 用间接免疫荧光与酶标法测定１０９例病毒性心肌炎（ＶＭＣ），５９例其它病患儿（ＣＯＤ）和６７名健康儿童（ＨＣ）血清中的心反应自身抗体和柯萨奇Ｂ组病毒１～６型的ＩｇＧ和ＩｇＭ抗体。采用Ｆｉｓｈｅｒ判别中的两类一般和逐步判别分析法，建立了各抗体联合判别儿童ＶＭＣ与ＣＯＤ及ＨＣ的一般和逐步判别方程１４个。结果表明：含全部抗体指标的两个一般判别方程一致率最高，其鉴别儿童ＶＭＣ与ＣＯＤ及ＮＣ的有效率分别为７９．２％和９２．１％。
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| 关 键 词： | 肌炎，柯萨奇病毒，抗体类，病毒，自身抗体，判别分析 |
THE DISCRIMINANT ANALYSIS OF SERUMANTIBODIES AND ITS DIAGNOSTIC VALUE IN VIRAL MYOCARDITIS OF CHILDREN |
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| Ouyang Fanxian.THE DISCRIMINANT ANALYSIS OF SERUMANTIBODIES AND ITS DIAGNOSTIC VALUE IN VIRAL MYOCARDITIS OF CHILDREN[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1996(6). |
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| Authors: | Ouyang Fanxian |
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| Abstract: | y using the indirect immunofluerescence and irnmunoenzyme assay,the authors detected theheart-reactive autoantibodies type IgG as well as the antibodies type IgG and IgM to coxsackievirus Type 1-6 Group B in the sera of 109 children with viral myocarditis(VMC),of 59 childrenwith other diseases(COD)and 67 healthy children(HC).Using two classes general and stepwisediscriminant analysis,the authors studied the united diagnostic value of the antibodies united in 6kinds of conbination and get 14 discriminant formulae.The results of the diagnostic value ofthese discriminants indicate that two formulae containing all of the 13 antibodies have the highestdiagnostic value;the consistency rates of differentiating VMC from COD and HC children are 79.2% and 92.1% respectively. |
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| Keywords: | myocarditis coxsackie virus antibodies viral autoantibodies diserimi-nant analysis |
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