| 虫草菌多糖保健粉的大鼠胚胎毒性和致畸性 |
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| 引用本文： | 杨萍,沈其萍,何丽芳. 虫草菌多糖保健粉的大鼠胚胎毒性和致畸性[J]. 现代预防医学, 2001, 28(3): 275-276 |
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| 作者姓名： | 杨萍 沈其萍 何丽芳 |
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| 作者单位： | 云南省卫生防疫站 |
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| 摘 要： | 目的：了解虫草菌多糖保健粉的大鼠胚胎毒性和对胎儿的致畸性。方法：应用传统致畸试验，结果：各剂量组胎鼠毒性和畸形与阴性对照组比较无显著性差异，而给予极高剂量（达5000 mg/kg.bw)时，孕鼠体重增重显著性低于阴性对照组，结论：虫草菌多糖保健粉对孕鼠体重增重有一定的影响，无胚胎毒性和致畸性。
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| 关 键 词： | 虫草菌多糖保健粉 胚胎毒性 致畸性 中药 |
| 文章编号： | 1003-8507(2001)03-0275-02 |
| 修稿时间： | 2000-11-15 |
THE EMBRYOTOXICITY AND TERATOGENICITY OF CORDYCEPS SINENSIS POLYGLUCOSE POWDER IN RATS |
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| Abstract: | Objective:The embryoxicity and teratogenicity studies of Cordyceps sinensis(Berk.) Sacc amylose powder were conducted in rats by traditional teratogenicity test.Result:The frequency of terates and the embryotoxicity of the fetus in each dose group were not significantly different as compared with negative control group.However,in very high dose(up to 5000mg/kg.bw),the growth of body weight in gestation of rats were significant lower than negative control.Conclusion:The Cordyceps sinensis(Berk.) Sacc amylose powder had slight effect on the body weight growth of pregnant rats,and possesses no embryotoxicity and teratogenicity. |
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| Keywords: | Cordyceps sinensis(Berk.) sacc amylose powder Embryotoxicity Teratogenicity |
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