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脂肪乳剂防治局部麻醉药中毒的研究进展
引用本文:孙斌,吴刚明,欧册华.脂肪乳剂防治局部麻醉药中毒的研究进展[J].医学综述,2013,19(3):467-469.
作者姓名:孙斌  吴刚明  欧册华
作者单位:泸州医学院临床医学院;泸州医学院附属医院麻醉科
基金项目:泸州医学院附属医院科研课题(11208)
摘    要:局部麻醉药中毒是临床上严重的麻醉并发症,虽然不常见,但是危害性极大,救治困难,尤其是局部麻醉药中毒导致的呼吸心搏骤停,应用传统救治方法救治困难。脂肪乳剂可逆转局部麻醉药中毒导致的毒性,并成功用于局部麻醉药中毒的解救。该文就脂肪乳剂防治局部麻醉药中毒的机制和临床应用进展予以综述,为今后脂肪乳剂解救局部麻醉麻药中毒及其临床应用方案提供依据。

关 键 词:脂肪乳剂  局麻药中毒  心搏骤停  心肺复苏

The Research Progress of Lipid Emulsion for Prevention of Local Anesthetic Toxicity
SUN Bin,WU Gang-ming,OU Ce-hua.The Research Progress of Lipid Emulsion for Prevention of Local Anesthetic Toxicity[J].Medical Recapitulate,2013,19(3):467-469.
Authors:SUN Bin  WU Gang-ming  OU Ce-hua
Institution:1.Clinical Institute of Luzhou Medical College,Luzhou 646000,China;2.Department of Anesthetics,Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China)
Abstract:Local anesthetic toxicity is a rare but severe anesthetic complication in clinical,especially the cardiac arrest,which is difficult to rescue with traditional treatment.Lipid emulsion can reverse the toxity of local anesthetic toxicity,and has been successfully applied.Here is to make a review on the research of mechanism and clinical application of lipid emulsion on resuscitation of local anesthetic toxicity to provide reference for the clinical solution in the future.
Keywords:Lipid emulsion  Local anesthetic toxicity  Cardioplegic  Cardiopulmonary resuscitation
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