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Effect of dietary cadmium intake on serum thyroxine and triiodothyronine concentrations in rhesus monkeys
Authors:J Mehta  D Dhawan  M Mehta  R Kumar  J S Chopra  R R Sharma
Affiliation:1. Departments of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh-160012 India;2. Departments of Biophysics, Postgraduate Institute of Medical Education and Research, Chandigarh-160012 India;3. Departments of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh-160012 India
Abstract:Circulating thyroxine (T4) and triiodothyronine (T3) concentrations in rhesus monkeys were determined after various periods of cadmium administration in diet. No significant change in serum T4 and T3 levels was observed after 2 months of cadmium treatment. However, cadmium treatment for 4 months and 6 months showed a significant decrease in serum T4 and T3 levels indicating the adverse effect of long-term cadmium intake which increased gradually with duration of treatment.
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