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Human Infection with Rickettsia felis, Kenya
Authors:Allen L. Richards   Ju Jiang   Sylvia Omulo   Ryan Dare   Khalif Abdirahman   Abdile Ali   Shanaaz K. Sharif   Daniel R. Feikin   Robert F. Breiman   M. Kariuki Njenga
Affiliation:Author affiliations: Naval Medical Research Center, Silver Spring, Maryland, USA (A.L. Richards, J. Jiang);;Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA (A.L. Richards);;US Centers for Disease Control and Prevention, Nairobi, Kenya (S. Omulo, R. Dare, D.R. Feikin, R.F. Breiman, M.K. Njenga);;Kenya Ministry of Health, Nairobi (K.A. Abdirahman, A. Ali, S.K. Sharif)
Abstract:To determine the cause of acute febrile illnesses other than malaria in the North Eastern Province, Kenya, we investigated rickettsial infection among patients from Garissa Provincial Hospital for 23 months during 2006–2008. Nucleic acid preparations of serum from 6 (3.7%) of 163 patients were positive for rickettsial DNA as determined by a genus-specific quantitative real-time PCR and were subsequently confirmed by molecular sequencing to be positive for Rickettsia felis. The 6 febrile patients’ symptoms included headache; nausea; and muscle, back, and joint pain. None of the patients had a skin rash.
Keywords:bacteria   Rickettsia felis   vector-borne infections   Rickettsia   Kenya   spotted fever group   rickettsiosis   flea-borne infections   quantitative PCR   research
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