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罗格列酮改善2型糖尿病患者血脂及蛋白尿的药理与临床研究
引用本文:杜明权,卢泽容,潘云影. 罗格列酮改善2型糖尿病患者血脂及蛋白尿的药理与临床研究[J]. 海南医学院学报, 2008, 14(4)
作者姓名:杜明权  卢泽容  潘云影
作者单位:深圳市福田区慢性病防治院,广东,深圳,518048
摘    要:目的:阐述罗格列酮改善2型糖尿病患者血脂及蛋白尿的药理,并进行临床观察。方法:选取糖尿病肾病且同时合并血脂异常的患者90例,设立自身对照组,加用罗格列酮12周,观察其对血脂及尿微量白蛋白的影响。结果:患者的血糖、血脂、微量白蛋白尿明显下降。结论:罗格列酮有较好的改善2型糖尿病患者血脂及蛋白尿的功效。

关 键 词:糖尿病,非胰岛素依赖型  高脂血症  尿  蛋白  药物疗法

Pharmacological and clinical research of rosiglitazone on Improving blood Lipids and proteinuria of the patients with Type 2 diabetes
DU Ming-quan,LU Ze-rong,PAN Yun-ying. Pharmacological and clinical research of rosiglitazone on Improving blood Lipids and proteinuria of the patients with Type 2 diabetes[J]. Journal of Hainan Medical College, 2008, 14(4)
Authors:DU Ming-quan  LU Ze-rong  PAN Yun-ying
Abstract:Objective:To explain pharmacological mechanism of rosiglitazone in improving blood lipids and proteinuria of the patients with type 2 diabetes and to undertake clinical observation.Methods:All 90 cases of the patients with diabetic nephropathy combined abnormal blood lipid level were treated rosiglitazone orally for 12 weeks self-control was designed and some indicators were obserred.Results:The levels of blood sugar,blood lipid and microalbuminuria were decreased significantly after the treatment.Conclusion:Rosiglitazone has better effects of improving blood lipids and proteinuria on the patients with type 2 diabetes.
Keywords:Diabetes,non-insulin dependance  Hyperlipemia  Urine  Protein  Drug therapy
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