| α-2b干扰素联合复方甘草酸苷治疗慢性丙型病毒性肝炎疗效观察 |
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| 引用本文： | 吴卫锋,孙薇薇.α-2b干扰素联合复方甘草酸苷治疗慢性丙型病毒性肝炎疗效观察[J].中国药房,2004,15(9):558-559. |
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| 作者姓名： | 吴卫锋 孙薇薇 |
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| 作者单位： | 南京市第二医院,南京市,210003 |
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| 摘 要： | 目的 :观察α -2b干扰素联合复方甘草酸苷治疗慢性丙型病毒性肝炎的效果。方法 :56例慢性丙型病毒性肝炎患者随机分为治疗组 (30例 )和对照组 (26例 )。治疗组给予α -2b干扰素 +复方甘草酸苷 ,对照组仅给予α -2b干扰素 ,疗程均为24周。结果 :治疗组治疗结束时及治疗结束后24周 ,ALT复常率与对照组比较均有显著性差异 (P<0 05) ,治疗组治疗结束时HCV -RNA转阴率与对照组比较有显著性差异 (P<0 05)。结论 :α -2b干扰素联用复方甘草酸苷可提高治疗慢性丙型病毒性肝炎的疗效
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| 关 键 词： | 慢性丙型病毒性肝炎 复方甘草酸苷 α-2b干扰素 |
| 文章编号： | 1001-0408(2004)09-0558-02 |
| 修稿时间： | 2004年4月19日 |
Therapeutic Effect of Ifα- 2b Plus Compound Glycyrrhizin on Chronic Hepatitis C |
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| WU Weifeng,SUN Weiwei.Therapeutic Effect of Ifα- 2b Plus Compound Glycyrrhizin on Chronic Hepatitis C[J].China Pharmacy,2004,15(9):558-559. |
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| Authors: | WU Weifeng SUN Weiwei |
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| Abstract: | OBJECTIVE:To observe the therapeutic effect of IF α-2b plus compound glycyrrhizin on chronic hepatitis C. METHODS:56cases of chronic hepatitis C were divided into trial group(30cases)and control group(26cases).Trial group received IF α-2b +compound glycyrrhizin and control group received IF α-2b alone.The therapeutic course was24weeks in both groups.RESULTS:There was significant difference in recoversion rate of ALT between two groups either at the end of therˉapeutic course or24weeks after treatment(P<0.05).The negative conversion rate of HCV-RNA in trial group was significa_ ntly different from that in control group(P<0.05).CONCLUSION:IF in combination with compound glycyrrhizin could improve the therapeutic effect on chronic hepatitis C. |
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| Keywords: | chronic hepatitis C compound glycyrrhizin IF |
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