| 雌激素对鼻粘膜影响的实验观察 |
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| 引用本文： | 赵秀杰,董震,杨占泉,赵德荣. 雌激素对鼻粘膜影响的实验观察[J]. 中华耳鼻咽喉头颈外科杂志, 1994, 0(2) |
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| 作者姓名： | 赵秀杰 董震 杨占泉 赵德荣 |
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| 作者单位： | 长春白求恩医科大学第一临床学院耳鼻咽喉科，吉林省人民医院耳鼻咽喉科 |
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| 摘 要： | 观察双侧卵巢切除和肌注雌二醇对雌性成龄脉鼠鼻粘膜的组织形态学影响。发现双侧卵巢切除的豚鼠的鼻粘膜呈退行性改变，包括纤毛崩解、脱落和腺体萎缩。肌注雌二醇豚鼠的鼻粘膜则表现为粘膜增厚，粘膜上皮下组织疏松和水肿，腺体增生，纤毛密集。提示不同水平雌激素对鼻粘膜有不同的作用。
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| 关 键 词： | 雌激素类，鼻粘膜 |
An Experimental Observation on the Influence of the Different Levels of Estradiol on the Nasal Mucosa |
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| Zhao Xiujie,Dong Zhen, Yang Zhanquan, el al. An Experimental Observation on the Influence of the Different Levels of Estradiol on the Nasal Mucosa[J]. Chinese journal of otorhinolaryngology head and neck surgery, 1994, 0(2) |
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| Authors: | Zhao Xiujie Dong Zhen Yang Zhanquan el al |
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| Abstract: | The histomorphological influences of ovariectomies and estradiol injections on the nasal mucosa were observed in adult female guinea pigs.In the mucosa of ovariectomized guinea pigs,degenerative changes including dissolving and desquamation of cilia and glandular hypotrophy were found.On the contrary,thickening layer of the epithelium,spongiosis and edema of the corium,hyperplasia of glands and increased density of cilia were observed in the mucosa of guinea pigs receiving estrogen. The results demonstrated that different levels of estrogen might have differents effects on the nasal mucosa. |
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| Keywords: | Estrogens Nasal mucosa |
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