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Thermoregulatory model for prediction of long-term cold exposure
Authors:Xu Xiaojiang  Tikuisis Peter  Gonzalez Richard  Giesbrecht Gordon
Affiliation:Biophysics and Biomedical Modeling Division, US Army Research Institute of Environmental Medicine, Kansas Street, Natick MA01760, USA. xiaojiang.xu@na.amedd.army.mil
Abstract:A multi-segmental mathematical model has been developed for predicting shivering and thermoregulatory responses during long-term cold exposure. The present model incorporates new knowledge on shivering thermogenesis, including the control and maximal limits of its intensity, inhibition due to a low core temperature, and prediction of endurance time. The model also takes into account individual characteristics of age, height, weight, % body fat, and maximum aerobic capacity. The model was validated against three different cold conditions i.e. water immersion up to 38 h and air exposure. The predictions were found to be in good agreement with the observations.
Keywords:Mathematical model   Thermoregulation   Shivering   Cold stress   Hypothermia
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