Spectrophotometric determination of <Emphasis Type="Italic">p</Emphasis>-aminophenol in drugs using 5,7-dichloro-4,6-dinitrobenzofuroxan reagent in micellar medium |
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Authors: | R F Bakeeva T S Gorbunova O E Vakhitova A I Gaisina L M Yusupova S Yu Garmonov V F Sopin |
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Institution: | (1) Kazan State Technological University, Kazan, Tatarstan, Russia; |
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Abstract: | A new spectrophotometric method for determining p-aminophenol in micellar aqueous dimethylsulfoxide (DMSO) media with non-ionogenic surfactant Triton X-100 that makes use
of 5,7-dichloro-4,6-dinitrobenzofuroxan as an indicator has been developed. Using the proposed method, it is possible to detect
an admixture of p-aminophenol in paracetamol (acetaminophen) in such media on a level that is much lower than the limiting concentration. The
presence of Triton X-100 in the form of micelles improves the sensitivity of spectrophotometric determination compared to
that of standard techniques. |
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Keywords: | |
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