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目的探讨GC护牙素与氟保护漆在正畸治疗中抑制牙釉质脱矿的临床效果。方法选择2011年1月至2012年9月在沈阳市口腔医院正畸科就诊的固定矫治患者117例共计2620颗牙齿，按就诊编号将患者随机分为3组。第1组患者（39例，868颗牙齿）矫治过程中左侧牙齿涂布GC护牙素，右侧牙齿涂布相似口味牙膏作为对照；第2组患者（39例，862颗牙齿）矫治过程中左侧牙齿涂布氟保护漆，右侧牙齿涂布釉质粘接剂A液作为对照；第3组患者（39例，890颗牙齿）矫治过程中左侧牙齿涂布GC护牙素，右侧牙齿涂布氟保护漆。GC护牙素的用法为患者每月复诊时涂布牙齿1次，氟保护漆的用法为患者每隔3个月复诊时涂布牙齿1次。观测记录3组患者矫治前、后的牙釉质脱矿情况，并对数据进行统计分析。结果第1组及第2组患者中涂布GC护牙素及氟保护漆侧牙齿的釉质脱矿指数明显低于对照侧，差异有统计学意义（P〈0．05）。第3组患者涂布GC护牙素侧牙齿的釉质脱矿指数与涂布氟保护漆侧的差异无统计学意义（P〉0．05）。结论GC护牙素及氟保护漆均能抑制正畸患者牙釉质脱矿，临床操作简便，疗效可靠。

Inhibitory effects of GC tooth mousse and fluoride varnish on enamel demineralization in orthodontic treatment.

Objective To evaluate the inhibitory effects of GC tooth mousse and fluoride varnish on enamel demineralization in orthodontic treatment. Methods A total of 117 patients with 2620 teeth were included. The patients were divided into 3 groups at random. The first group included 39 patients with 868 teeth： the teeth on the left were given GC tooth mousse every month, and the teeth on the fight were given toothpaste as the control group. The second group included 39 patients with 862 teeth： the teeth on the left were given fluoride varnish every 3 months and the teeth on the right were given A of enamel adhesive as the control group. The third group included 39 patients with 890 teeth： the teeth on the left were given GC tooth mousse every month, while the teeth on the opposite were applied with fluoride varnish every 3 months. The enamel demineralization was observed during treatment and the data were analyzed. Results The enamel decalcification index of study group was significantly lower than that of control group in the first and second group（P 〈 0.05）. In the third group there was no significant difference between GC tooth mousse group and fluoride varnish group （P 〉 0.05）. Conclusion GC tooth mousse and fluoride varnish have a positive effect on the prevention of enamel demineralization during fixed orthodontic treatment.