| 74例结核分枝杆菌耐药情况分析 |
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| 引用本文： | 兰 萍刘 梅李娜娜王建华陈 玲. 74例结核分枝杆菌耐药情况分析[J]. 中国现代医生, 2018, 56(1): 130-132 |
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| 作者姓名： | 兰 萍刘 梅李娜娜王建华陈 玲 |
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| 作者单位： | 遵义医学院珠海校区;遵义医学院附属医院呼吸医学研究室; |
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| 基金项目： | 贵州省科学技术基金项目（黔科合J字[2012]2354号） |
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| 摘 要： | 目的了解遵义地区结核分枝杆菌耐药情况,并探讨其耐药特点,为耐药结核病的监测提供参考。方法采用比例法对我院门诊及住院的肺结核患者痰标本中分离到的74株结核分枝杆菌进行异烟肼、利福平、链霉素和乙胺丁醇4种一线抗结核药物的敏感性试验。结果 74例肺结核患者结核分枝杆菌对一线抗结核药的总耐药率为54.1%,耐多药率为12.2%。结论本地区结核分枝杆菌耐药情况严重,应进一步加强耐药结核的监测。
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| 关 键 词： | 结核分枝杆菌；药物敏感试验；耐药率；监测 |
Analysis of drug resistance in 74 cases of mycobacterium tuberculosis |
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| LAN PingLIU MeiLI NanaWANG JianhuaCHEN Ling. Analysis of drug resistance in 74 cases of mycobacterium tuberculosis[J]. , 2018, 56(1): 130-132 |
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| Authors: | LAN PingLIU MeiLI NanaWANG JianhuaCHEN Ling |
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| Affiliation: | 1.Zhuhai Campus,Zunyi Medical University,Zhuhai 519041,China;2.Research Office of Respiratory Medicine,Zunyi Medical University Affiliated Hospital,Zunyi 563003,China |
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| Abstract: | Objective To understand the drug resistance of mycobacterium tuberculosis in Zunyi and explore the characteristics of its drug resistance,so as to provide a reference for the surveillance of drug-resistant tuberculosis.Methods 74 strains of mycobacterium tuberculosis isolated from sputum samples of outpatients and inpatients in our hospital were given sensitivity test of 4 kinds of first-line anti-TB drugs,including isoniazid,rifampicin,streptomycin and ethambutol.Results The total drug resistance rate of mycobacterium tuberculosis to first-line anti-tuberculosis drugs in 74 patients with pulmonary tuberculosis was 54.1%,and multi drug resistance rate was 12.2%.Conclusion The drug resistance of mycobacterium tuberculosis in this area is serious,and the surveillance of drug-resistant TB should be further strengthened. |
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| Keywords: | Mycobacterium tuberculosis Drug sensitivity test Drug resistance rate Surveillance |
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